Bookedited by J. David Sweatt, Michael J. Meaney, Eric J. Nestler.
Summary: Behavioral Epigenetics is the study of how environmental factors affect alterations in behavior, addressing the fundamental mechanisms that shape development and individual vulnerability/resilience to adverse behavioral outcome. With an understanding of the molecular mechanisms involved in epigenetic modulation, researchers believe it will be possible to develop targeted therapies for those individuals in whom it malfunctions. This volume will address current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior.
Contents:
An overview of the molecular basis for epigenetics / J. David Sweatt ... [et al.]
Histone modifications in the nervous system and neuropsychiatric disorders / Morgan Bridi, Ted Abel
Active DNA demethylation and 5-hydroxymethylcytosine / Junjie U. Guo, Guo-li Ming, Hongjun Song
The epigenetics of parental effects / Tie Yuan Zhang ... [et al.]
Epigenetic mechanisms in learning and memory / Jeremy J. Day, J. David Sweatt
Drug addiction and reward / Alfred J. Robinson, Jian Feng, Eric J. Nestler
The mind and it's nucleosomes: chromatin (dys)regulation in major psychiatric diseases / Rahul Bharadwaj, Cyril J. Peter, Schahram Akbarian
HDAC inhibitors as novel therapeutics in aging and Alzheimer's disease / Alexi Nott ... [et al.]
miRNAs and neurodevelopmental disorders / Quan LIn, Yi E. Sun
Imprinting the CNS and neurodevelopment disorders / Weston T. Powell, Janine M. LaSalle
Neuronal genomic and epigenetic diversity / Michael J. McConnell, Fred H. Gage
Adult neurogenesis / Jenny Hsieh, Hongjun Song
Trangenerational inheritance in mammals / Isabelle M. Mansuy, Rahia Mashoodh, Frances A. Champagne
Epigenetics: defining the frontiers of genomic function / Michael J. Meaney ... [et al.]