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  • Book
    Celine Bicquart Ord, Eric K. Hansen, Charles R. Thomas, Jr, editors.
    Contents:
    Central Nervous System Tumors: Adult and Pediatric
    Skin Cancer
    Head and Neck Cancer
    Lung Cancer
    Tumors of the Mediastinum
    Breast Cancer
    Upper Gastrointestinal Cancers
    Lower Gastrointestinal Cancers
    Urinary System Cancers
    Male Genitourinary Cancer
    Gynecologic Malignancies
    Hematologic Malignancies
    Sarcoma
    Pediatric Non-central Nervous System Cancers
    Benign and Metastatic Disease.
    Digital Access Springer 2013
  • Article
    Ting CC.
    J Natl Cancer Inst. 1978 Feb;60(2):437-44.
    Cytotoxic T (thymus)-lymphocytes (CTL) with specific cytotoxicity against the leukemia-associated antigens of FBL-3, a syngeneic Friend virus-induced leukemia in C57BL/6 mice, could be adoptively transferred to sublethally X-irradiated (350 R) syngeneic hosts and could be induced by adoptive transfer of either normal or presensitized lymphocytes obtained from immunocompetent hosts. The CTL and their precursor cells were systemically distributed in peripheral lymph nodes and spleen, although they had the tendency of homing to the lymphoid tissue of the same origin. Direct cytotoxicity was obtained with the lymphocytes from these lymphoid tissues, and cells obtained from these lymphoid tissues could produce secondary cytotoxic responses by the mixed lymphocyte tumor cell culture reactions 40--60 days after adoptive transfer. In addition, lymph node and spleen cells had a synergistic effect on the induction of cytotoxicity. These findings indicated that tumor immunity was widely distributed and that various populations of lymphocytes were involved in the generation of efficient cell-mediated cytotoxic responses.
    Digital Access Access Options