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- BookHelmut Breuninger, Patrick Adam.Contents:
Introduction
The Basics for Excision and Flattening
Embedding and Sectioning
Dividing Tumors and Topographical Orientation
Communication with the Lab
The Aftermath or How to Excise Until Clear Margins
Variations for Special Locations and Large, Deep Penetrating Tumors
How to Perform 3D Histology on Different Types of Tumors
Terminology and Facts.Digital Access Springer 2013 - ArticlePencek TL, Schauf CL, Davis FA.J Pharmacol Exp Ther. 1978 Feb;204(2):400-5.Haloperidol (Haldol) selectively inhibits sodium currents at the voltage-clamped node of Ranvier at concentrations ranging from 0.013 to 13 muM. The action potential is reduced or abolished while the membrane potential is not significantly changed. The dose-response curve is described by a Langmuir adsorption isotherm with an apparent dissociation constant of 6 X 10(-7) M. Sodium current time-to-peak and the permeability-voltage relationship are not affected, although at higher concentrations the inactivation time constant is slightly increased. Potassium currents are not altered except at 13 muM where there is an occasional nonsystematic effect. Leakage currents are not changed at any concentration.