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- BookVictoria A. Harden.Summary: Society was not prepared in 1981 for the appearance of a new infectious disease, but we have since learned that emerging and reemerging diseases will continue to challenge humanity. This work is the first history of HIV/AIDS written for a general audience that emphasizes the medical response to the epidemic. The author, a medical historian approaches the AIDS virus from philosophical and intellectual perspectives in the history of medical science, discussing the process of scientific discovery, scientific evidence, and how laboratories found the cause of AIDS and developed therapeutic interventions. Furthermore, her book places AIDS as the first infectious disease to be recognized simultaneously worldwide as a single phenomenon. After years of believing that vaccines and antibiotics would keep deadly epidemics away, researchers, doctors, patients, and the public were forced to abandon the arrogant assumption that they had conquered infectious diseases. By presenting a discussion of the history of HIV/AIDS and analyzing how aspects of society advanced or hindered the response to the disease, the book illustrates how medicine identifies and evaluates new infectious diseases quickly and what political and cultural factors limit the medical community's response.
Contents:
Emerging in silence
What Is this new disease?
Searching for the cause of AIDS
Clinical research, epidemic of fear, and AIDS in the worldwide blood supply
AIDS as a cultural phenomenon
AIDS therapy
Communicating AIDS
The global epidemic
The third decade. - ArticleMalyzhev VA.Tsitologiia. 1977 Jul;19(7):832-6.The preincubation of mouse spleen lymphocytes with a low molecular lymphocytosis-stimulating substance from the thymus (LSS), or the addition of the LSS to the cultures caused inhibition of the mitotic response of lymphocytes to phytohemagglutinin (PHA). LSS induced transformation of murine thymocytes to the blast cells capable of mitotic division. This transformation was depressed by PHA. The lymphocytes of the mice injected LSS in vivo responded weakly to PHA at first, but in 5 days a significant intensification on the response to PHA was observed. It is concluded that LSS may activate the T-cells responding to PHA.