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- ArticleStewart TH, Hollinshead AC, Harris JE, Raman S, Bélanger R, Crépeau A, Crook AF, Hirte WE, Hooper D, Klaassen DJ, Rapp EF, Sachs HJ.Can J Surg. 1977 Jul;20(4):370-7.A radomized clinical trial of chemotherapy, immunization and immunochemotherapy among 55 patients with stages I and II carcinoma of the lung is reported. The survival rate in the immunized groups was significantly better (P = 0.001) than that in the nonimmunized groups. The results are discussed in the light of the reactivity of the patients to the specific cancer antigen.