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- JournalDigital Access Asian Pac J Allergy Immunol v. 1-, 1983-
- ArticleMakarenko IuA, Karpovich EA, Sheresheva EL, Khvastunov RM.Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Mar-Apr;27(2):282-8.The manifestation of some signs of emotional reactions produced by stimulation of the hypothalamic zones through implanted electrodes was studied in chronic experiments on 8- to 40-day old rats. Beginning with the 12th day of the rats' development, the formation of the instrumental reaction of self-stimulation and avoidance was studied. It has been found that maturation of the negative emotion mechanism preceds that of the positive emotion mechanism. Proceeding from the results obtained, a hypothesis has been advanced on heterochronous maturation of the systems of positive and negative reinforcements. It has been assumed that beginning with certain stage of the animals' development, behaviour is being controlled with the participation of a non-specific "reward" mechanism.