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- Bookedited by Andrian Carter, Wayne Hall, Judy Illes.Contents:
What is addiction neuroethics and why does it matter?
Brain Imaging in Addiction
Molecular Neuroscience and Genetics
Treating Opioid Dependence with Opioids: Exploring the Ethics
Addiction Neuroscience and Tobacco Control
Emerging Neurobiological Treatments of Addiction: Ethical and Public Policy Considerations
Technical, Ethical and Social Issues in the Bioprediction of Addiction Liability and Treatment Response
Autonomy, Responsibility and the Oscillation of Preference
Consent and Coercion in Addiction Treatment
Toward a Lay Descriptive Account of Identity in Addiction Neuroethics
The Impact of Changes in Neuroscience and Research Ethics on the Intellectual History of Addiction Research
The Diction of Addiction at the Intersection of Law and Neuroscience
Social Epistemology: Communicating Neuroscience
Population Approaches to Alcohol, Tobacco and Drugs: Effectiveness, Ethics and Interplay with Addiction Neuroscience
Legal Regulation of Addictive Substances and Addiction
Investment and Vested Interests in Neuroscience Research of Addiction: Ethical Research Requires More than Informed Consent
Private and Public Approaches to Addiction Treatment: Evidence and Beliefs.Digital Access ScienceDirect 2012 - ArticleRafferty NS, Goossens W.Am J Anat. 1977 Mar;148(3):385-407.Normal and needle-punctured lenses of Rana pipiens were examined with the electron microscope in order to characterize the sequence of ultrastructural changes that follow the injury over a 5-month period. Results were compared with those obtained previously in experimentally injured mouse and accidentally injured human lenses. The normal adult frog lens was found to have a morphology similar to that of mammalian lenses. As in the human, frog lens epithelial cells contained scattered microfilaments and were connected by desmosomes and gap junctions. They differed from mouse cells, which had been shown to lack desmosomes and to have microfilaments organized into dense bundles. These differences are postulated to be related to the degree of accommodative deformation of the lens displayed by these species. After injury, cellular debris and fibrin, accumulated in the wound, were phagocytized by extrinsic cells derived from the blood and ocular tissues. Leucocytes, pigmented cells and fibroblasts remained in the wound for eight weeks, along with epithelial cells which proliferated and migrated from the wound margins.Epithelial cells showed an increase in those organelles associated with protein synthesis and transport, and in microfilaments. In cataractous lenses, epithelial cells showed changes in matrix, and lens fibers became organized into smaller, denser compressed units. At five months, considerable healing had taken place, but localized opacities persisted in many frog lenses.