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- ArticleNaeim F, Leibold W, Gatti R, Walford RL.Transplant Proc. 1977 Mar;9(1 Suppl 1):151-5.Twenty lymphoblastoid cell lines were typed with 38 antisera defining the 13 groups of the Merrit B-cell alloantigenic system, and results were compared with those of a 20-member CLL cell panel. While overall pattern of Merrit groups for the two types of cell population was similar, some sera in a number of groups showed unexpected negative cytotoxic reactions with lymphoid cells compared to other sera of the same group. However, in a number of instances, these negatively reacting cells could still specificity absorb out tb Merrit antibodies, suggesting that lymphoblastoid lines may show a higher incidence of the CYNAP (cytotoxicity-negative-absorption-positive) phenomenon than CLL cells. Twelve of the lymphoblastoid lines were HLA-D homozygous and in addition, each cell line displayed positive reactions for no more than 2 of the 13 Merrit groups, while 4 of the 8 heterozygous lines were positive for 3 of the 13 groups. These findings indicate that HLA-D-homozygous cell lines are antigenically simpler than the heterozygous lines for the Merrit system and suggest that HLA-D-homozygosity may correlate with homozygosity for at least one of the Merrit loci.
- Bookedited by John Cameron, Paul Hunter, Paul Jagals and Katherine Pond.Summary: "This publication addresses the broader issues of social cost-benefit analysis performed on options to invest in drinking-water supplies, with a focus on small community suppliers"--Back cover.
Contents:
The practice of economic assessment of small-scale drinking-water interventions / John Cameron and Paul Jagals
Economic assessments of improvements in drinking-water supply - the global evidence / Chris Edwards and John Cameron
Current situation in access to drinking-water / Katherine Pond and Stephen Pedley
Defining the current situation - epidemiology / Paul R Hunter and Helen Risebro
Defining the current situation - observing livelihoods / John Cameron
Interventions for water provision / Stephen Pedley, Katherine Pond and Eadaoin Joyce
Estimating the costs of small-scale water-supply interventions/ Paul Jagals and Luuk Rietveld
Estimating health impacts of interventions with a focus on small-scale drinking-water interventions / Helen Risebro and Paul R. Hunter
Cost-effectiveness analysis in practice / Chris Edwards
Social cost-benefit analysis - principles / John Cameron
Social cost-benefit analysis - summarizing the available global evidence on drinking-water interventions / Chris Edwards.Digital Access WHO 2011