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  • Book
    edited by Roland T. Skeel, Samir N. Khleif.
    Contents:
    SECTION I: BASIC PRINCIPLES AND CONSIDERATIONS OF RATIONAL CHEMOTHERAPY AND MOLECULAR THERAPY
    1. Biologic and pharmacologic basis of cancer chemotherapy / Roland T. Skeel
    2. Biologic basis of molecular targeted therapy / Osama E. Rahma, Samir N. Khleif
    3. Systemic assessment of the patient with cancer and consequences of treatment / Roland T. Skeel
    4. Selection of treatment with the patient with cancer / Roland T. Skeel
    SECTION II: CHEMOTHERAPY AND MOLECULAR THERAPY OF HUMAN CANCER
    5. Carcinonas of the head and neck / Barbara A. Murphy
    6. Carcinomas of the lung / David E. Gerber, Joan H. Schiller
    7. Carcinomas of the gastrointestinal tract / Maxwell Vergo, AI B. Benson III
    8. Carcinomas of the pancreas, liver, gallbladder, and bile ducts / Timothy J. Kennedy, Steven K. Libutti
    9. Carcinomas of the breast / Patrick Glyn Morris, Clifford A. Hudis
    10. Gynecologic cancer / Thomas McNally, Richard T. Penson, Chau Tran, Michael J. Birrer
    11. Urologic and male genital cancers / Brendan D. Curti, Craig R. Nichols
    12. Kidney cancer / Mark T. Andolina, Colleen Darnell, Olivier Rixe
    13. Thyroid and adrenal cancinomas / Haitham S. Abu-Lebdeh, Michael E. Menefee, Keith C. Bible
    14. Melanomas and other cutaneous malignancies / Ragini Kudchadkar, Jeffrey S. Weber
    15. Primary and metastatic brain tumors / April Fitzsimmons Eichler, Tracy T. Batchelor
    16. Soft tissue sarcomas / Robert S. Benjamin
    17. Bone sarcomas / Robert S. Benjamin
    18. Acute leukemias / Olga Frankfurt, Martin S. Tallman
    19. Chronic leukemias / Khaled el-Shami, Bruce D. Cheson
    20. Myeloproliferative neoplasms and myledysplastic syndromes / Elias Jabbour, Hagop Kantarjian
    21. Hodgkin lymphoma / Richard S. Stein, David S. Morgan
    22. Non-Hodgkin lymphoma / Mark Roschewski, Wyndham H. Wilson
    23. Multiple myeloma, other plasma cell disorders, and primary amyloidosis / Rachid Baz, Mohamad A. Hussein
    24. Metastatic cancer of unknown origin / James M. Leonardo
    25. HIV-associated malignancies / Thomas S. Uldrick, Mark N. Polizzotto, Robert Yarchoan
    SECTION III: SUPPORTIVE CARE OF PATIENTS WITH CANCER
    26. Side effects of chemotherapy and molecular targeted therapy / Janelle M. Tipton
    27. Infections: etiology, treatment, and prevention / Thomas J. Walsh, Joan M. Duggan
    28. Transfusion therapy, bleeding, and clotting / Mary R. Smith, NurJehan Quraishy
    29. Oncology emergencies and critical care issues: spinal cord compression, cerebral edema, Superior Vena Cava Syndrome, anaphylaxis, respiratory failure, Tumor Lysis Syndrome, hypercalcemia, and bone metastasis / Roland T. Skeel
    30. Malignant pleural, peritoneal, and pericardial effusions and meningeal infiltrates / Rekha T. Chaudhary
    31. Cancer pain / Richard T. Lee, Michael J. Fisch
    32. Emotional and psychiatric problems in patients with cancer / Kristi Skeel Williams, Kathleen S.N. Franco-Bronson
    SECTION IV: CHEMOTHERAPEUTIC AND MOLECULAR TARGETED AGENTS AND THEIR USE
    33. Classification, use, and toxicity of clinically useful chemocherapy and molecular targeted therapy / Roland T. Skeel
    Appendix A: Nomogram for determining body surface area of adults from height and mass
    Appendix B: Nomogram for determining boy surface area of children from height and mass.
    Digital Access Ovid 2011
  • Article
    Hann HW, London WT, Evans AE.
    Cancer. 1977 May;39(5):2001-3.
    In previous reports, children with acute lymphoblastic leukemia (ALL), who presented with T-cell markers on their lymphoblasts (T-lymphoblasts), have been predominantly older boys often with a mediastinal mass. These children are thought to constitute a subgroup of childhood ALL that has the poorest prognosis. Here, we report five girls with ALL, who presented with T-lymphoblasts but without a mediastinal mass. All responded well to chemotherapy and three of five are in maintained remission 21-33 months after diagnosis. The fourth patient died while in remission of causes other than leukemia and the fifth relapsed and died of infection two years after diagnosis. These observations suggest that girls with T-lymphoblasts may not have an adverse prognosis.
    Digital Access Access Options