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- ArticleKarsenti E, Guilbert B, Bornens M, Avrameas S.Ann Immunol (Paris). 1977 Jan-Mar;128(1-2):195-200.The preparation and the purification of anti-action and anti-tubulin antibodies is reported. The occurrence of low amount of IgG anti-tubulin was also found in the sera of non-immunized animals from various species. The staining of the cellular network of microtubules as well as of tubulin paracrystals was observed with both induced and natural antibodies.