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- ArticleStanulla H.Zentralbl Allg Pathol. 1977;121(1-2):108-13.Report of a 21-year old male with biopsy-proved (primary) isolated Histiocytosis X (eosinophilic granuloma) localized in the lungs. The disease prefers young males and leads to a non-characteristical fibrosis of the lung in cases of chronical course. Lung biopsy is the only certain method for diagnosis. Morphology, differential-diagnosis and aetiology of this rare disease are also considered.