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  Creating infrastructures for Latino mental health

  Lydia P. Buki, Lissette M. Piedra, editors ; foreword by Melba J.T. Vasquez.

  Contents:
  Latinos and the Changing Demographic Landscape: Key Dimensions for Infrastructure Building --Latino Mental Health: Acculturation Challenges in Service Provision
  Building Response Capacity: The Need for Universally Available Language Services
  Increasing Service Parity Through Organizational Cultural Competence
  Building Infrastructure Through Training and Interdisciplinary Collaboration
  Investing in the Future: Expanding Educational Opportunities for First-Generation Latino College Students
  Putting Students to Work: Spanish Community Service Learning as a Countervailing Force
  Serving Latino Families Caring for a Person with Serious Mental Illness
  The Plight of Latino Youth in the Juvenile Justice System: Considerations for Mental Health Treatment
  Promoting the Well-Being of Unaccompanied Immigrant Minors
  Latinos in Rural Areas: Addressing Mental Health Disparities in New Growth Communities
  Life During and After Breast Cancer: Providing Community-based Comprehensive Services to Latinas
  Lessons Learned from HIV Service Provision: Using a Targeted Behavioral Health Approach
  Private Practice with Latinos: Brief Reflections and Suggestions.

  Digital Access Springer 2011
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• Article

  Induction of cell-mediated immunity to chemically modified antigens in guinea pigs. II. The interaction between lipid-conjugated antigens, macrophages, and T lymphocytes.

  Dailey MO, Post W, Hunter RL.

  J Immunol. 1977 Mar;118(3):963-70.

  Protein antigens covalently conjugated with lipid groups (dodecanoic acid) have previously been shown to stimulate strong delayed-type hypersensitivity (DTH) without the aid of adjuvants. The present experiments show that lipid-conjugated bovine serum albumin (L-BSA) is taken up in vitro by macrophages (Mpsi) 25- to 50-fold more than unconjugated BSA or aminidated BSA, neither of which induces DTH. Macrophages that take up 125I-labeled L-BSA in vitro stimulate DTH even more efficiently, when injected into syngeneic guinea pigs, than does soluble L-BSA. Tracer studies on the fate of radiolabeled BSA and L-BSA showed that much more L-BSA than BSA was retained by draining lymph nodes. Autoradiography demonstrated that 125I-L-BSA is rapidly taken up by Mpsi in the medullary sinuses of the lymph nodes. Some of this antigen is then transported into the paracortex, a region in which T lymphocytes predominate. The capacity of lipophilic antigens to stimulate cell-mediated immune responses may be caused by their increased uptake by Mpsi, resulting in more efficient presentation to immunocompetent T lymphocytes. The anatomical site of this Mpsi-T cell interaction may be within the sinusoids or paracortex of the draining lymph nodes.

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  PubMed