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  • Journal
    Digital Access Project Euclid v. 1-, 1973-
  • Article
    Eriksson B, Hedfors E.
    Scand J Haematol. 1977 Feb;18(2):121-8.
    Changes in numbers of peripheral blood lymphocytes from healthy individuals were calculated from samples collected before and after parenteral administration of adrenaline, insulin and hydrocortisone, respectively. A marked increase in circulating lymphocytes was noted in response to adrenaline and insulin. However, subpopulation analysis showed a decrease in the proportion of T-lymphocytes, estimated as cells forming rosettes with sheep red blood cells after incubation in the cold and a corresponding increase in proportion of lymphocytes having receptors for C3 (non-T lymphocytes). In contrast, lymphocyte numbers were unaffected by hydrocortisone. The results indicate that a decreased proportion of circulating T-lymphocytes and an increase of non-T-lymphocytes may be the result of adaptive changes in response to various forms of stress and hence is to be expected in several clinical conditions.
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