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  • Book
    Malcolm Rowland, Thomas N. Tozer.
    Summary: This edition has been retitled Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications to reflect the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response and also reflects the expansion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs.

    Contents:
    Therapeutic relevance
    Fundamental concepts and terminology
    Kinetics following an intravenous bolus dose
    Membranes and distribution
    Elimination
    Kinetics following an extravascular dose
    Absorption
    Response following a single dose
    Therapeutic window
    Constant-rate input
    Multiple-dose regimens
    Variability
    Genetics
    Age, weight, and gender
    Disease
    Nonlinearities
    Drug interactions
    Initiating and managing therapy
    Distribution kinetics
    Metabolites and drug response
    Protein drugs
    Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    2011
    RM301.5 .R68 2011
    1