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  • Book
    [edited by] Donglu Shi.
    Contents:
    Stem Cells and Nanostructured Materials / Vince Beachley and Xuejun Wen
    Biomedical Polymer Nanofibers for Emerging Technology / Kwideok Park, Won Ho Park, Jun Sik Son and Dong Keun Han
    Nanoscale Mechanisms for Assembly of Biomaterials / Zhijie Sui and William L. Murphy
    Fabrication and Assembly of Nanomaterials and Nanostructures for Biological Detections / Qingkai Yu and Jie Lian
    Nanostructured Materials Constructed from Polypeptides / Peng Jing, Jangwook P. Jung and Joel H. Collier
    Photoluminescent Carbon Nanomaterials: Properties and Potential Applications / Yaping Sun, Fushen Lu, Xin Wang, Li Cao and Yi Lin, et al.
    Microwave-assisted Synthesis and Processing of Biomaterials / Yingjie Zhu and Jiang Chang
    Characterizing Biointerfaces and Biosurfaces in Biomaterials Design / Kalpana S. Katti, Devendra Verma and Dinesh R. Katti
    Carbon Nanotubes for Electrochemical and Electronic Biosensing Applications / Ningyi Liu, Qing Zhang, Mary B Chan-Park, Changming Li and Peng Chen
    Heparin-Conjugated Nanointerfaces for Biomedical Applications / Ki Dong Park, Yoon Ki Joung, Jin Woo Bae and Dong Hyun Go
    Inorganic Nanoparticles for Biomedical Applications / Mei Chee Tan, Gan Moog Chow, Lei Ren and Qiqing Zhang
    Nano Metal Particles for Biomedical Applications / Kyung A. Kang, Bin Hong and Hanzhu Jin
    Micro- and Nanoscale Technologies in High-Throughput Biomedical Experimentation / Vikramaditya G. Yadav, Mark D. Brigham, Ling Yibo, Christopher Rivest and Utkan Demirci, et al.
    Delivery System of Bioactive Molecules for Regenerative Medicine / Gilson Khang, Yoon Sun Jung, Soon Hee Kim, Moon Suk Kim and Hai Bang Lee
    Modification of Nano-sized Materials for Drug Delivery / Tao Xu, Heather L. Nichols, Ning Zhang and Xuejun Wen
    Polymeric Nano Micelles as a Drug Carrier / Moon Suk Kim, Hyun Hoon, Gilson Khang and Hai Bang Lee
    DNA Nanotechnology / Junping Zhang and Roger J. Narayan
    Nanoscale Bioactive Surfaces and Endosseous Implantology / Yunzhi Yang, Yongxing Liu, Sangwon Park, Hyunseung Kim and Kwangmin Lee, et al.
    Carbon Nanotube Smart Materials for Biology and Medicine / Yeo Heung Yun, Vesselin N. Shanov, Adam Bange, William R. Heineman and H. Brian Halsall, et al.
    Microscopic Modeling of Phonon Modes in Semiconductor Nanocrystals / Wei Cheng, Shangfen Ren and David T. Marx
    Fracture Processes in Advanced Nanocrystalline and Nanocomposite Materials / I. A. Ovid'ko
    Synthesis, Properties and Application of Conducting PPY Nanoparticles / Xingui Li, Meirong Huang and Yunbin Xie
    Field Emission of Carbon Nanotubes / Baoqing Zeng and Zhifeng Ren
    Flexible Dye-Sensitized Nano-Porous Films Solar Cells / Dongshe Zhang, Tony Pereira, Torsten Oekermann, Katrin Wessels and Changyong Qin, et al.
    Magnetic Nanofluids: Synthesis and Structure / L. Vékás, M. V. Avdeev and Doina Bica.
    Digital Access Springer 2009
  • Article
    Kaufman RJ, Brown PC, Schimke RT.
    Proc Natl Acad Sci U S A. 1979 Nov;76(11):5669-73.
    Selection of mammalian cells in progressively increasing concentrations of methotrexate results in selective amplification of DNA sequences coding for dihydrofolate reductase (tetrahydrofolate dehydrogenase, 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase, EC 1.5.1.3). In some cell variants the amplified genes are stable with growth in the absence of methotrexate, whereas in other variants the amplified genes are lost from the population. We have previously reported that in a stably amplified variant of Chinese hamster ovary cells, the genes are localized to a single chromosome. Herein we report that in mouse S-180 and L5178Y cell lines unstably amplified dihydrofolate reductase DNA sequences are associated with small, paired chromosomal elements denoted "double minute chromosomes," whereas in stably amplified cells of the same origin, the genes are associated with large chromosomes.
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