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- BookNándor Ács, Ferenc G. Bánhidy, Andrew E. Czeizel.Contents:
The Hungarian congenital abnormality registry (HCAR)
Certain infectious and parasitic diseases
Neoplasms
Diseases of the blood and blood-forming organs
Endocrine, nutritional and metabolic diseases
Mental and behavioural disorders
Diseases of the nervous system
Diseases of the eye and adnexa
Diseases of the ear and the mastoid process
Diseases of the circulatory system
Diseases of the respiratory system
Diseases of the digestive system
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system and connective tissue
Diseases of the urinary tract
Diseases of the genital organs
Pregnancy, childbirth, and the puerperium
Congenital malformations, deformations, and chromosomal abnormalities
Association of maternal diseases during pregnancy with higher risk of congenital abnormalities (CAs) in their children
Associations of maternal diseases with higher risk for preterm birth (PB) and low birth weight (LBW) newborns.Digital Access Springer 2010 - ArticleAlsabti EA.Neoplasma. 1979;26(5):611-5.Forty-five patients with acute myelogenous leukemia have been followed sequentially for 12 months. All these patients had serum immunoglobulin IgA, IgG, IgM and IgE levels measured by immunodiffusion and radioimmunoassay prior to chemotherapy, then every month after chemotherapy. Significant differences were found in IgA and IgG levels prior chemotherapy, while no differences were found in IgM or IgE levels at any time. There was a positive correlation between percentage of blasts and IgA level. There was negative correlation between the percentage of blasts and IgM levels. These findings raise the value of measuring the levels of immunoglobulins in patients with leukemia as a guide to the subclinical relapse of the disease. These results may also support the hypothesis of the role of early immune defect in immunoglobulin metabolism in the pathogenesis of acute leukemia.