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  • Book
    Haiyong Han, Paul Grippo, editors.
    Contents:
    1. Drug evaluations in pancreatic cancer culture systems
    2. Mouse xenograft models for drug discovery in pancreatic cancer
    3. Flourescent metastatic mouse models of pancreatic cancer for drug discovery
    4. A new preclinical paradigm for pancreas cancer
    5. Zebrafish as a biological system for identifying and validating therapeutic targets and compounds
    6. Gene expression arrays in pancreatic cancer drug discovery research
    7. Using array comparative genomic hybridization of pancreatic cancer samples to map interesting regions for target gene identification
    8. The application of high-throughput RNAi in pancreatic cancer target discovery and drug development
    9. MicroRNA a profiling and its application in drug discovery in pancreatic cancer
    10. Methylation detection and epigenomics in pancreatic cancer
    11. Tissue microarray applications in drug discovery for pancreatic cancer
    12. Proteomic analysis of blood and pancreatic juice
    13. Applications of antibody-lectin sandwich arrays (ALSA) to pancreatic cancer diagnostics and drug discovery
    14. The development of pharmacodynamic endpoint models for evaluation of therapeutic in pancreatic cancer
    Index.
    Digital Access Springer 2010
  • Article
    Clark GT, Beemsterboer PL, Solberg WK, Rugh JD.
    J Am Dent Assoc. 1979 Oct;99(4):607-11.
    Twenty-five patients with symptoms of myofascial pain and abnormal jaw function were treated with use of a full arch maxillary occlusal splint. The level of nocturnal activity of the masseter muscle was monitored as were symptoms before, during, and after occlusal splint therapy. A decreased nocturnal EMG level during treatment was noted for 52% of the patients. A return to pretreatment EMG levels after removal of the splint was noticed in 92% of the patients; in 28% no change was shown and in 20%, an increase was shown in nocturnal EMG levels. The splint was most likely to reduce nocturnal EMG levels in patients with least severe symptoms.
    Digital Access Access Options