Live Chat
Today's Hours: 8:00am - 8:00pm
Lane Medical Library

Search

Filter Results

Did You Mean:

Search Results

Sort by
relevance
  • Journal
    Digital Access ACS v. 56-100, 1952-96.
  • Article
    Chowhan ZT.
    J Pharm Sci. 1978 Sep;67(9):1257-60.
    The solubilities of naproxen, 7-methylsulfinyl-2-xanthonecarboxylic acid, 7-methylthio-2-xanthonecarboxylic acid, and their sodium, potassium, calcium, and magnesium salts were determined as a function of pH. The results on the solubility of naproxen and its salts were in excellent agreement with the theoretical profiles describing the relationship between pH values of the solutions and the dissociation constant of the acid. The solubilities of the two xanthonecarboxylic acids were higher at higher pH values than the values calculated when complete dissociation in solution was assumed. The influence of the salt species on the solubility of organic carboxylic acids, at and above pH values of complete ionization, cannot be predicted even qualitatively from equations used for alkali and alkaline earth metal salts.
    Digital Access Access Options