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  • Book
    edited by Terence A. Ketter.
    Contents:
    Principles of assessment and treatment of bipolar disorders / Terence A. Ketter
    DSM-IV-TR diagnosis of bipolar disorders / Terence A. Ketter, Po W. Wang
    Addressing clinical diagnostic challenges in bipolar disorders / Terence A. Ketter, Po W. Wang
    Multiphase treatment strategy for bipolar disorders / Terence A. Ketter, Po W. Wang, Jenifer L. Culver
    Overview of pharmacotherapy for bipolar disorders / Terence A. Ketter, Po W. Wang
    Management of acute manic and mixed episodes in bipolar disorders / Terence A. Ketter, Po W. Wang
    Management of acute major depressive episodes in bipolar disorders / Po W. Wang, Terence A. Ketter
    Longer-term management of bipolar disorders / Terence A. Ketter, Po W. Wang
    Management of rapid-cycling bipolar disorders / Terence A. Ketter, Po W. Wang
    Management of bipolar disorders in children and adolescents / Kiki D. Chang ... [et al.]
    Management of bipolar disorders in women / Laurel N. Zappert, Natalie L. Rasgon
    Management of bipolar disorders in older adults / John O. Brooks III, Barbara R. Sommer, Terence A. Ketter
    Mood stabilizers and antipsychotics : pharmacokinetics, drug interactions, adverse effects, and administration / Terence A. Ketter, Po W. Wang
    Antidepressants, anxiolytics/hypnotics, and other medications : pharmacokinetics, drug interactions, adverse effects, and administration / Terence A. Ketter, Po W. Wang
    Adjunctive psychosocial interventions in the management of bipolar disorders / Jenifer L. Culver, Laura C. Pratchett.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RC516 .H357 2010
    1
  • Article
    Robinson JW, Alvarado F.
    J Neural Transm Suppl. 1979(15):125-37.
    The kinetics of the influx of tryptophan and phenylalanine into guinea-pig intestinal rings have been examined. The transfer of these two amino acids can be described by a single transport system, each amino acid having an affinity constant, Kt, of about 4 mM for the influx mechanism. Mutual inhibition studies have shown that the inhibitory constant of each of the amino acids is also 4 mM. Although fully competitive inhibition between the two amino acids occurs, the inhibition of the influx of the amino acids by sugars exhibits kinetics of the "pseudo-competitive" type. Such behaviour is compatible with an allosteric interaction between two different binding sites, one for each class of compounds. The lack of correlation between the inhibitory potency of a given sugar and its rate of transfer, as testified by a comparison of the effects of galactose and beta-methyl-glucoside on phenylalanine influx, can be reconciled with the "allosteric-interaction hypothesis", but specifically repudiates any theory that attempts to explain such interactions in a way that requires such a correlation. The fact that allosteric interactions are retained in cells preloaded with sodium also precludes a primary role for sodium in the mechanism of such interactions.
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