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- Bookvolume editor, Allen F. Ryan.Contents:
Gene therapy for the inner ear : challenges and promises / Ryan, A.F., Dazert, S.
Therapeutic regulation of gene expression in the inner ear using RNA interference / Maeda, Y., Smith, R.J.H.
Gene therapy of the inner ear using adenovirus vectors / Husseman, J., Raphael, Y.
Repair of the vestibular system via adenovector delivery of Atoh1 : a potential treatment for balance disorders / Baker, K., Brough, D.E., Staecker, H.
Gene therapy and stem cell transplantation : strategies for hearing restoration / Kesser, B.W., Lalwani, A.K.
Adenoviral and AAV-mediated gene transfer to the inner ear : role of serotype, promoter, and viral load on in vivo and in vitro infection efficiencies / Luebke, A.E. ... [et al.].Digital Access Karger 2009Access via Advances in oto-rhino-laryngology ; 2009; 66LocationVersionCall NumberItems - ArticleLund O, Høyvik H.Acta Otolaryngol Suppl. 1979;360:113-5.Patients with selective hearing loss in the trebles, as commonly seen in acoustic trauma, often have a considerable hearing handicap. They seldom benefit from the usual hearing aids with closed ear moulds. When Ewertsen (1970) and Cortois (1972) reported their experiences with binaural fitting of hearing spectacles, using a free plastic tube in the ear canal ("no mould"), we at the Hearing Centre in Namsos began to fit such hearing aids to 33 patients with acoustic traumas. All of them were followed-up in February--March 1978. The results have been evaluated on the basis of answers from the patients entered on questionnaires, and speech audiometry in open field, monosyllable, with 60 dB wide-band background noise. 27 patients (80%) stated that they were greatly satisfied, and 7 (20%) well satisfied. The average daily use was 4 1/2 hrs. All of the patients emphasized the great benefit obtained with the hearing aid at conferences, meetings, social occasions, etc. The average hearing gain was 13 dB. Among those who had discrimination loss there was an average gain of 30% .