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  Anais da Faculdade de Medicina da Universidade Federal de Minas Gerais

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  v. 23-27, 30-31, 1966/67-1970, 1973-74.

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• Article

  G6PD Vientiane: a new glucose-6-phosphate dehydrogenase variant with increased stability.

  Kahn A, North ML, Cottreau D, Giron G, Lang JM, Oberling F.

  Hum Genet. 1978 Jul 12;43(1):85-9.

  A new G6PD variant, called G6PD Vientiane, has been discovered in a patient from Laos. The characteristics of this variant are: mild enzyme deficiency (about 50% of the normal activity) in the granulocytes and the red cells, with normal G6PD-related antigen concentration; increased stability; normal Km glucose 6-phosphate and NADP+; increased inhibition constant by NADPH; decreased inhibition by ATP; slightly increased utilization of the substrate analogue; abnormal pH curve, with maximum activity at pH 9.5; slightly reduced starch gel electrophoretic migration. The implications of the molecular stability of a deficient mutant variant are discussed.

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• Book

  Population Growth and Economic Development with Special Reference to Pakistan; : Summary Report of a Seminar Organized by the Institute of Development Economics, Karachi, in Cooperation with the Population Council, New York, September 8-13, 1959

  M. L. Qureshi, editor.

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