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  • Journal
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    Stored offsite. Please request print.
    v. 3-19, [20], 1949-65, [1966].
    15
  • Article
    Koehler KA, Jain MK, Stone EE, Fossel ET, Koehler LS.
    Biochim Biophys Acta. 1978 Jun 16;510(1):177-85.
    Fluorine-19 nuclear magnetic resonance spectroscopy is applied to the study of the environment of dipalmitoyl phosphatidylcholine-bound fluorinated ether anesthetics (enflurane, fluoroxene and methoxyflurane) both below and above the lipid gel to liquid crystal phase transition temperature. Line widths and spin-lattice relaxation time (T1) measurements are consistent with substantial immobilization of the lipid-bound anesethetic molecules. Heating anesthetic/lipid mixtures above the lipid transition temperature leads to narrowing of the lipid-bound anesthetic fluorine resonances accompanied by little or no change in anesthetic fluorine-19 chemical shifts, suggesting that although the mobility of the bound anesthetic increases at the higher temperature, the nature of the anesthetic-lipid interaction changes little as a result of this phase change. Differential scanning calorimetric studies of the effects of these anesthetics on the phase transition behavior of the phospholipid indicate that the regions of the bilayer in which volatile anesthetics partition at lower concentrations are different from the regions in which they partition at higher concentrations.
    Digital Access Access Options
  • Book
    as told by the people and written by members of the Federal Writers' Project of the Works Progress Administration in North Carolina, Tennessee and Georgia.
    Contents:
    On the farm
    In mill village and factory
    In service occupations
    On relief.
    Print 1939