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- ArticleFriedhoff AJ, Miller JC, Weisenfreund J.Am J Psychiatry. 1978 Aug;135(8):952-5.The authors compared platelet monoamine oxidase activity in drug-free chronic and acute schizophrenic patients, medicated chronic schizophrenic patients, and normal controls. A significant decrement in MAO activity was found only in medicated chronic schizophrenic patients. The possible mechanism for this finding is discussed.