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  • Book
    Buros, Oscar Krisen; Carlson, Janet F.; Conoley, Jane Close; Geisinger, Kurt F.; Impara, James C.; Kramer, J. J.; Mitchell, James V.; Plake, Barbara S.; Spies, Robert A.
    Digital Access
    Provider
    Version
    Ovid
    Database Limited to 4 simultaneous users
    Ovid
    Test reviews online Limited to 4 simultaneous users
    Print Access Request
    Location
    Version
    Call Number
    Items
    Retired Reference (Downstairs)
    1949-2010.
    Z5814.P8 M4
    19
  • Article
    Birch CG, Hiles RA, Eichhold TH, Jeffcoat AR, Handy RW, Hill JM, Willis SL, Hess TR, Wall ME.
    Drug Metab Dispos. 1978 Mar-Apr;6(2):169-76.
    3,4,4'-Trichlorocarbanilide (TCC), uniformly labeled with 14C in the monochloro ring, was administered to rats, rhesus monkeys, and humans. Radioactive materials in the plasma and urine of all three species and in the bile of rats and monkeys were separated by high performance liquid chromatography. The chromatography showed great similarity between the monkey and the human. Principal metabolites common to all species were the sulfate and glucuronide conjugates of 2'-, 3'-, and 6-hydroxy-TCC. The rat also produced the glucuronide and sulfate conjugates of 2',6-dihydroxy-TCC. The major urinary excretion products found in humans and monkeys were the N- and N'-TCC glucuronides.
    Digital Access Access Options