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  • Database
    Summary: World's largest compilation of chemical facts used for planning synthetic routes (including starting materials and intermediates), determining bioactivity and physical properties and ascertaining the environmental fates of compounds.
    Digital Access Elsevier MDL Database
  • Article
    Palkovits M, Kobayashi RM, Kizer JS, Jacobowitz DM, Kopin IJ.
    Neuroendocrinology. 1975;18(2):144-53.
    The effects of acute stress on norepinephrine (NE) and dopamine (DA) concentrations and of repeated stress on tyrosine hydroxylase (TH) activity were measured in individual hypothalamic nuclei and other rat brain regions. A microdissection technique and radioisotopic enzymatic assays enables these studies to be performed. NE and DA concentrations were reduced and TH activity increased selectively in the arcuate nucleus. These results suggest that the arcuate nucleus may be selectively involved in the stress response and support the hypothesis that catecholamines in the medial basal hypothalamus mediate certain of the neuroendocrine changes observed in stress.
    Digital Access Access Options