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  • Journal
    Digital Access ScienceDirect v. 1-, 2006-
  • Book
    edited by Peter N. Nemetz.
    Summary: As the importance of the Pacific Rim as a global centre of large-scale investment, development and trade continues to increase, so do the potential benefits. This book integrates a broad range of current economic data concerning the Pacific Rim with some of the more important theoretical issues in the area of economic development and trade. It demonstrates the paradoxical combination of strength and fragility that characterizes the emerging integrated Pacific Rim economy and attempts to clarify the nature of the framework and constraints that face foreign investors and trading partners. The historical background of Japan's trade with other Pacific nations is examined in the opening chapter, which is complemented by a new article outlining in detail the nature of, and rationale for, the profound change in Japan's foreign direct investment in the 1980s. Other articles analyse trade in the ASEAN countries -- Indonesia, Malaysia, the Philippines, Singapore, and Thailand -- and discuss the emerging financial centres in the Pacific Rim. "Peter N. Nemetz is an associate professor in the policy analysis division of the Faculty of Commerce and Business Administration at the University of British Columbia. He is also the editor of the "Journal of Business Administration. Nielsen 9780774803601 20160528

    Contents:
    Contributors: Peter N. Nemetz, Yoko Sazanami, Tracy Redies, Rodney Tyers, Prue Phillips, Theodore Panayotou, Gavin Boyd, Alan M. Rugman, Alain Verbeke, Colin Dodds, Kam-Hon Lee, Ilan Vertinsky, Charles J. Johnson, Allen L. Clark, Robert N. Yanover, Joy Dunkerley, Douglas Bohi, Vaclav Smil, Harold Halvorson, David L. Anderson, Yasumasa Kuroda, Fereidun Fesharaki, Wendy Schultz, Kirk R. Smith. Nielsen 9780774803601 20160528
    Print ©1990
  • Article
    Saito H, Ratnoff OD.
    J Lab Clin Med. 1975 Mar;85(3):405-15.
    Although surface contact is known to accelerate the one-stage prothrombin time of human plasma through the participation of Hageman factor (factor XII) and factor VII, it has not been clear whether Hageman factor interacts with factor VII directly or indirectly. Recently, Gjønnaess reported experiments suggesting that plasma kallikrein was an intermediate between Hageman factor and factor VII. The present study was undertaken to elucidate the interaction of plasma kallikrein and factor VII. Incubation of Fletcher-trait plasma (deficient in a plasma prekallikrein) with kaolin at 0 degrees C. did not induce shortening of the Thrombotest time or enhancement of factor VII activity, in contrast to studies of normal plasma. Monospecific rabbit antiserum against plasma kallikrein blocked the shortening of the Thrombotest time of normal plasma brought about by kaolin. Purified Hageman factor fragments (prekallikrein activator) induced an increase in factor VII activity in normal or Hageman-trait plasma, but not in Fletcher-trait plasma. A purified plasma kallikrein preparation enhanced factor VII activity in all plasmas, including that of Fletcher-trait plasma. The effect of the kallikrein preparation was blocked by soybean trypsin inhibitor, Trasylol, or rabbit antiserum against kallikrein, but not by lima bean trypsin inhibitor or antiserum against Hageman factor. The activity of partially purified factor VII was enhanced by purified kallikrein in the presence, but not in the absence of factor VII-deficient plasma. These results further support the idea that the enhancement of factor VII activity by surface contact is via Hageman factor and plasma kallikrein, suggesting a possible link between the intrinsic and extrinsic pathway of blood clotting. The significance of this phenomenon in hemostasis in vivo remains to be elucidated.
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