Search
Filter Results
- Resource Type
- Article1
- Journal1
- Journal Digital1
- Result From
- Lane Catalog1
- PubMed1
-
Year
- Journal Title
- IARC Sci Publ (1971)1
Search Results
Sort by
- JournalDigital AccessProviderVersionOvidAcad Search Prem
- ArticleHinuma Y, Sairenji T, Maeda M.IARC Sci Publ (1971). 1978(20):385-90.Investigations were carried out on newly synthesized MA, VCA and EA in Daudi cells superinfected with the P3HR-1 strain of EBV and treated with trypsin to remove previously adsorbed MA-positive material from the cell surface. Synthesis of MA, VCA and EA was completely blocked by puromycin. A marked reduction in the frequency of MA-positive cells was observed in the infected cell cultures in the presence of either Ara-C or PA, but a fraction of the MA-positive cells was insensitive to the inhibitors. Differential absorption of an EBV antibody-positive human serum with Ara-C-treated or -untreated infected cells revealed two antigenically different components of MA: early (Ara-C-insensitive) and late (Ara-C-sensitive) MA. Three of five sera from patients with NPC, but none of five sera from normal adults, showed an apparent 'prozone' phenomenon in their reactivity against late but not early MA.