Search

Search Results

• Journal

  Bio-medical materials and engineering

  Digital Access Acad Search Prem v. 7, no. 6-, 1997-

  Full text delayed 9 months
  Get Shareable Link

  View Details
• Article

  Decreased serum cholesterol-binding reserve in diabetes mellitus.

  Hsia SL, Fishman LM, Briese FW, Christakis G, Burr J, Bricker LA.

  Diabetes Care. 1978 Mar-Apr;1(2):89-93.

  Serum cholesterol-binding reserve (SCBR), the capacity of a serum sample to solubilize additional cholesterol in excess of its cholesterol content, was measured in 43 white male patients with maturity-onset diabetes in the age range of 35--59 years who were under treatment with insulin. The values were compared with those of 194 nondiabetic controls of the same race, sex, and age range. The mean +/- S.D. of SCBR of patients (71.9 +/- 29.3 mg./dl.) was lower than that of controls (88.9 +/- 30.9 mg./dl.) (p less than 0.001). Age in the range of 35 to 59 years had no correlation with SCBR in either patients or controls. SCBR was positively correlated with serum levels of cholesterol (SC) and triglycerides (TG) in both patients and controls. After adjustment for SC and TG, the difference in SCBR between patients and controls persisted (p less than 0.001). In 15 of 20 (75 per cent) patient-control pairs matched for SC and TG to within 5 per cent, the patient had lower SCBR (paired t-test, p less than 0.002). In 16 patients without elevation of serum lipid levels (SC below 250 and TG below 150 mg./dl.), the mean +/- S.D. of SCBR (59.1 +/- 17.7 mg./dl.) was lower than that of 49 controls having serum lipids in the same range (77.4 +/- 31.7 mg./dl.) (p less than 0.03). These results indicate an association of decreased SCBR with diabetes and are consistent with the hypothesis that low SCBR is associated with accelerated atherosclerosis and enhanced risk for coronary heart disease.

  Digital Access Access Options
  Get Shareable Link

  PubMed
• Book

  An account of the exercises on the occasion of the presentation of the Langley medal and the unveiling of the Langley memorial tablet, May 6, 1913,

  including the addresses of Dr. Alexander Graham Bell, His Excellency, the French ambassador, Mons. J. J. Jusserand, Dr. John A. Brashear, and Secretary Walcott ...

  Print 1913
  Get Shareable Link

  View Details