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- ArticleWu CF, Ganetzky B, Jan LY, Jan YN, Benzer S.Proc Natl Acad Sci U S A. 1978 Aug;75(8):4047-51.A mutant, napts (no action potential, temperature-sensitive), is described in which axonal conduction fails at high temperature. Synaptic transmission at the larval neuromuscular junction is unimpaired. Larvae and adults are rapidly paralyzed at restrictive temperatures; they recover rapidly when the temperature is decreased. The mutant gene is recessive and is located on the second chromosome at map position 56.