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- ArticleSoria J, Soria C, Samama M.Pathol Biol (Paris). 1976 Dec;24(10):725-9.A simple, rapid and sensitive spectrophotometric method for the evaluation of plasminogen level is presented. After activation of plasminogen by streptokinase, plasmin is determined using its amidasic action on a tripeptidic substrate bound with paranitroanlin.