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  • Book
    von Otto Bütschli...
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    D1505 .B92 1924
    1
  • Article
    Jackson JF, North ER, Thomas JG.
    Clin Genet. 1976 May;9(5):483-7.
    A physical examination checklist of 25 signs of Down's syndrome was used to predict the presence of absence of 21-trisomy in 291 individuals examined for suspected Downs syndrome. Using only total numbers of signs present, 21-trisomy was unambiguously predicted in about half those examined. Discriminant analysis using the most informative 10 signs misclassified only 11 of 169 infants aged 2 years or less, and allowed non-overlapping classification into Down's and non-Down's of almost three-fourths of suspected individuals. The risk for Down's syndrome in the overlap area was 58%.
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