BookRobert A. Weinberg, Massachusetts Institute of Technology ; with chapters by Richard Goldsby, Amherst College, Michael Hemann, Massachusetts Institute of Technology, Tyler Jacks, Massachusetts Institute of Technology
Summary: "The gold standard text in cancer biology, thoroughly updated with the latest research. Incorporating the most important advances in the rapidly-evolving field of cancer biology, this book remains the defining course text on its subject. Students, instructors, researchers, and clinicians the world over admire its authoritative content, clear explanations, extensive full-color art program, and pedagogical features that promote a deep conceptual understanding of the science through the lens of fascinating tales of scientific discovery"-- Back cover
Contents:
The biology and genetics of cells and organisms
The nature of cancer
Cancer as an Infectious Disease
Cellular oncogenes
Growth factors, receptors, and cancer
Cytoplasmic signaling circuitry programs many of the traits of cancer
Tumor suppressor genes
pRB and control of the cell cycle clock
p53: Master Guardian and Executioner
Eternal life : cell immortalization and tumorigenesis
Multi-step tumorigenesis
Shaping and Characterizing the Cancer Genome
Dialogue replaces monologue : heterotypic interactions and the biology of angiogenesis
Moving out : invasion and metastasis
Crowd control : tumor immunology
Cancer Immunotherapy
The rational treatment of cancer
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