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  • Article
    Jaswal V, J RB, N YK.
    Chemosphere. 2023 Jul;330:138556.
    Nano-bedecking of electrode with nanoparticles is an effective method to improve power generation of microbial fuel cells (MFCs). In this study, different concentrations (0.25 mg cm-2, 0.50 mg cm-2, 0.75 mg cm-2 and 1.0 mg cm-2) of TiO2 nanoparticles of size 10-25 nm were overlaid on the carbon cloth (CC) using spray pyrolysis technique and used as catalytic cathode in a dual-chambered microbial fuel cell treating distillery wastewater. Results evidenced that TiO2 nanoparticles modified cathode increased the power generation and recorded a highest power and current density of 162.5 ± 2 mW m-2 and 1.4 ± 0.005 A m-2, respectively. Carbon cloth coated with 0.50 mg cm-2 TiO2 nanoparticles showed 2.8 and 7.3 times higher current and power density as compared to uncoated cathode. MFC operated at a hydraulic retention time (HRT) and organic loading rate (OLR) of 72 h and 59.2 g COD L-1 d-1 showed a maximum chemical oxygen demand (COD) removal of 72.3% which was 15.3% higher than the control MFC. Likewise, the coulombic efficiency of control and modified MFC was 33% and 44%, respectively. The maximum NO3-- N, NO2-- N and NH4+- N removal efficiency of 77.3%, 49.9% and 59.4% were observed for TiO2 nanoparticles modified electrode which was 19.3%, 11.4% and 10.5% higher than control. TiO2 modified cathode was effective in enhancing the bioelectricity generation in MFCs.
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  • Article
    Luo X, Cao L, Yu L, Gao M, Ai J, Gao D, Zhang X, John Lucas W, Huang S, Xu J, Shang Y.
    Food Chem. 2024 Jun 15;443:138556.
    Potato is one of the most important crops worldwide, to feed a fast-growing population. In addition to providing energy, fiber, vitamins, and minerals, potato storage proteins are considered as one of the most valuable sources of non-animal proteins due to their high essential amino acid (EAA) index. However, low tuber protein content and limited knowledge about potato storage proteins restrict their widespread utilization in the food industry. Here, we report a proof-of-concept study, using deep learning-based protein design tools, to characterize the biological and chemical characteristics of patatins, the major potato storage proteins. This knowledge was then employed to design multiple cysteines on the patatin surface to build polymers linked by disulfide bonds, which significantly improved viscidity and nutrient of potato flour dough. Our study shows that deep learning-based protein design strategies are efficient to characterize and to create novel proteins for future food sources.
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  • Article
    Wachtel MS, Yang S, Dissanaike S, Margenthaler JA.
    PLoS One. 2015;10(9):e0138556.
    PURPOSE: A decline in breast cancer incidence has been attributed to the reduction in hormone replacement therapy (HRT) prescriptions since the publication of the landmark WHIT paper in 2003. Concurrently, a relationship between HRT and cerebrovascular disease incidence has also been suggested. No generalized analysis of HRT prescription rates and breast cancer incidence rates that included more than seven years of data. We hypothesized that detailed analysis of SEER data would clarify the relationship between HRT use and breast cancer incidence. Given the large decline in HRT prescription rates uncovered, analyses of potential complications were also conducted, with the understanding that a small effect or one limited to a subpopulation, such as a single race, might not be detected.
    METHODS: Incidence rates (per 100,000 women) and standard errors for ductal and lobular breast carcinomas, and endometrioid /endometrial carcinomas in women over 50 years were obtained from the Surveillance, Epidemiology, and End Results (SEER) database 1992-2012. From the Medical Expenditure Panel Survey 1996-2012 weighted counts and standard errors of hormone replacement therapy (HRT) prescriptions for women over 50 years were obtained. Using the National Hospital Discharge Survey (NHDS), 1996-2010 weighted counts and standard errors of femoral neck fractures, total hip replacements, acute myocardial infarctions, and cerebral infarctions were obtained for 50+ year men and women. Weighted counts and standard errors were divided by US census figures and multiplied by 100,000. Joinpoint regression was used to analyze rates.
    MAIN RESULTS: Beginning 2001, HRT prescription rates dropped dramatically, 2001-2012 AAPC -14.9 (95% CI -17.4, -12.4). Breast cancer rates, which began to decline in 1999, increased after 2003; 2012 rates were similar to those seen in 2001 for both ductal, AAPC 0.1 (-0.4, 0.6) and lobular, AAPC 0.5 (-0.4, 1.5), carcinoma. Endometrial carcinoma rates increased, 2001-2012 AAPC 3.5 (3.1, 3.8), arguing against a negative effect of HRT discontinuation of endometrial carcinoma. Tests for parallelism failed to detect APC differences among genders for femoral neck fractures (P = 0.24), for total hip replacements (P = 0.11), for myocardial infarctions (P = 0.10), or for cerebral infarctions (P = 0.19), precluding any assignment of general effect on these disorders by HRT.
    CONCLUSIONS: Using SEER data, we demonstrated that changes in breast cancer rates cannot be explained by HRT prescription rate changes.
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  • Article
    Wang L, Zhou Y, Lei X, Zhou Y, Bi H, Mao XZ.
    Sci Total Environ. 2020 Jul 15;726:138556.
    Predicting disastrous wind and rainfall associated with tropical cyclones (TCs) is critical to prevent and mitigate the casualties and damage of TCs. The studied warning area was chosen with a radius of 800 km centered on Hong Kong in which the tracks of TCs making landfall in China are concentrated. In general, the number of TCs making landfall decreased but landfall locations and intensities of TCs increased since 1990. Our results suggested minimum sea level pressure (MSLP) in TC affected areas was the predominant disaster-warning factor and indicator for the resulting risks and damages of TCs in 1975-2017. The MSLP of 990 hPa monitored in a TC affected area was a threshold for severe impacts and prediction of strong wind and heavy rainfall. Early warning using a combination of MSLP and the nearest approach distance of TCs (MSLP of 990 hPa for distance of 100 km) outperformed the current warning system based on wind speed, often providing more timely warning and reducing the false warnings.
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  • Article
    Noor AA, Khan MA, Zhang Y, Lv K, Sun J, Liu C, Li MC.
    Int J Biol Macromol. 2024 Dec 08;287:138556.
    Drilling fluids are often referred to as the "blood" of the drilling process, as they play a crucial role in determining both the efficiency and safety of drilling operations. Natural polymers, derived from renewable sources, such as cellulose, lignin, chitosan, xanthan gum, and starch, offer inherent advantages such as sustainability, biodegradability, and environmentally-friendliness when used as additives in drilling fluids. However, the inherent properties of natural polymers are adversely affected by thermal degradation due to their low heat resistance under harsh drilling conditions, where temperatures can exceed 150 °C. To address these challenges, various modification techniques, including free radical polymerization, esterification, etherification, silanization, hydroxymethylation, and ionic crosslinking, have been employed. This paper provides an overview of recent advances in the application of modified natural polymers as additives in water-based drilling fluids (WBDFs) under high-temperature drilling conditions. It begins by discussing the degradation mechanisms of natural polymers at high temperatures, followed by a review of the techniques used for their modification. Subsequently, the application of modified natural polymers as rheological and fluid loss additives in high-temperature WBDFs is briefly presented. Finally, the challenges, environmental impacts, and future considerations for the use of modified polymers are outlined to guide future development of environmentally friendly, high-performance WBDFs.
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  • Book
    [edited by] Anne Griffin Perry, Patricia A. Potter, Wendy R. Ostendorf.
    Summary: Clinical Nursing Skills & Techniques offers clear and comprehensive coverage of over 200 basic, intermediate and advanced skills. Features nearly 1,000 full-color photographs and drawings, a nursing process framework, step-by-step instructions with rationales, and a focus on critical thinking and evidence-based practice. This edition also includes new coverage of patient-centered care and safety guidelines, an enhanced emphasis on QSEN core competencies, and an expanded clinical focus with specialized Clinical Debriefs, Teach-Back, and sample documentation throughout.

    Contents:
    Supporting the patient through the health care system
    Vital signs and physical assessment
    Special procedures
    Infection control
    Activity and mobility
    Safety and comfort
    Hygiene
    Medications
    Oxygenation
    Fluid balance
    Nutrition
    Elimination
    Care of the surgical patient
    Dressings and wound care
    Home care
    Appendixes.