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  • Article
    Sfara V, Mougabure-Cueto GA, Zerba EN, Alzogaray RA.
    PLoS One. 2013;8(12):e83433.
    N,N-diethyl-3-methylbenzamide (DEET) is the active principle of most insect repellents used worldwide. However, its toxicity on insects has not been widely studied. The aim of this work is to study the effects of DEET on the locomotor activity of Blattella germanica. DEET has a dose-dependent repellent activity on B. germanica. Locomotor activity was significantly lower when insects were pre-exposed to 700 µg/cm(2) of DEET for 20 or 30 minutes, but it did not change when pre-exposure was shorter. Locomotor activity of insects that were pre-exposed to 2.000 µg/cm(2) of DEET for 10 minutes was significantly lower than the movement registered in controls. No differences were observed when insects were pre-exposed to lower concentrations of DEET. A 30-minute pre-exposure to 700 µg/cm(2) of DEET caused a significant decrease in locomotor activity. Movement was totally recovered 24 h later. The locomotor activity measured during the exposure to different concentrations of DEET remained unchanged. Insects with decreased locomotor activity were repelled to the same extent than control insects by the same concentration of DEET. We demonstrated that the repellency and modification of locomotor activity elicited by DEET are non-associated phenomena. We also suggested that the reduction in locomotor activity indicates toxicity of DEET, probably to insect nervous system.
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  • Book
    [edited by] Caroline S. Zeind, Michael G. Carvalho, Judy W. Cheng, Kathy Zaiken, Trisha LaPointe.
    Summary: "Continually revised and updated for 50 years, Applied Therapeutics: The Clinical Use of Drugs is the gold standard for patient centered drug therapeutics. With its acclaimed case-based approach, it promotes mastery and application of the fundamentals of drug therapeutics. Featuring contributions from more than 200 experienced clinicians, every chapter reflects our ever-changing knowledge of drugs and the application of this knowledge to the individualized therapy of patients. As students progress from the General Principles section to chapters on specific diseases, they will benefit from practical problem-solving techniques that help devise effective evidence-based drug treatment plans"-- Provided by publisher.

    Contents:
    Section 1: General principles. Medication therapy management and assessment of therapy ; Interpretation of clinical laboratory tests ; Drug interactions ; Pharmacogenomics and personalized medicine ; Managing drug overdoses and poisonings ; End-of-life care ; Interprofessional practice and education
    Section 2: Cardiac and vascular disorders. Dyslipidemias, atherosclerosis, and coronary heart disease ; Essential hypertension ; Peripheral vascular disorders ; Thrombosis ; Chronic stable angina ; Acute coronary syndrome ; Heart failure ; Cardiac arrhythmias ; Hypertensive crises ; Shock
    Section 3: Pulmonary disorders. Asthma ; Chronic obstructive pulmonary disease ; Acute and chronic rhinits ; Cystic fibrosis
    Section 4: Gastrointestinal disoders. Nausea and vomiting ; Upper gastrointestinal disorders ; Lower gastrointestinal disorders ; Complications of end-stage liver disease
    Section 5: Renal disorders. Acid-base disturbances ; Fluid and electrolyte disorders ; Chronic kidney disease ; Acute kidney injury ; Dialysis treatment for chronic kidney failure ; Dosing of drugs in kidney failure
    Section 6: Immunologic disorders. Drug hypersensitivity reactions ; Systemic lupus erythematosus ; Kidney and liver transplantation
    Section 7: Nutrition issues. Basics of nutrition and patient assessment ; Obesity ; Adult enteral nutrition ; Adult parenteral nutrition
    Section 8: Dermatologic disorders. Dermatotherapy and drug-induced skin disorders ; Acne ; Psoriasis ; Photosensitivity, photoaging, and burn injuries
    Section 9: Rheumatic and musculoskeletal diseases. Osteoarthritis ; Rheumatoid arthritis ; Gout and hyperuricemia ; Connective tissue disorders
    Section 10: Women's health. Contraception ; Infertility ; Obstetric drug therapy Disorders related to the menstrual cycle ; The transition through menopause
    Section 11: Endocrine disorders. Thyroid disorders ; Diabetes mellitus. Section 12: Eye disorders. Eye disorders
    Section 13: Neurologic disorders. Pain and its management ; Care of the critically ill adult ; Mutiple sclerosis ; Headache ; Parkinson disease and other movement disorders ; Seizure disorders ; Acute ischemic and hemorrhagic stroke
    Section 14: Infectious diseases. Principles of infectious diseases ; Antimicrobial prophylaxis for surgical procedures ; Vaccinations ; Central nervous system infections ; Endocarditis ; Respiratory tract infections ; Tuberculosis ; Infectious diarrhea ; Intra-abdominal infections ; Urinary tract infections ; Sexually transmitted diseases ; Osteomyelitis and septic arthritis ; Skin and soft tissue infections ; Prevention and treatment of infections in neutropenic cancer patients ; Pharmacotherapy of human immunodeficieny virus infection ; Opportunistic infections in patients living with HIV ; Fungal infections ; Viral infections ; Viral hepatitis ; Parasitic infections ; Tick-borne diseases
    Section 15: Psychiatric disorders and substance abuse. Anxiety disorders ; Sleep disorders ; Schizophrenia ; Depressive disorders ; Bipolar disorders ; Developmental disorders ; Attention-deficit hyperactivity disorder in children, adolescents, and adults ; Substance use disorders ; Tobacco use and dependence
    Section 16: Hematology and oncology. Anemias ; Neoplastic disorders and their treatment: general principles ; Adverse effects of chemotherapy, immunotherapy, and targeted agents ; Pediatric malignancies ; Adult hematologic malignancies ; Breast cancer ; Lung cancer ; Colorectal cancer ; Prostate cancer ; Hematopoietic stem cell transplantation
    Section 17: Pediatrics. Pediatric pharmacotherapy ; Pediatric fluid, electrolytes, and nutrition ; Common pediatric illnesses ; Neonatal therapy ; Care of the critically ill child
    Section 18: Geriatric therapy. Geriatric drug use ; Geriatric neurocognitive disorders ; Geriatric urologic disorders ; Osteoporosis.
    Print Access Request
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    Books: General Collection (Downstairs)
    RM262 .A65 2024
    2