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- ArticleErvasti J, Vahtera J, Pentti J, Oksanen T, Ahola K, Kivimäki M, Virtanen M.PLoS One. 2013;8(11):e79855.OBJECTIVE: Depression is a major cause of disability in working populations and the reduction of socioeconomic inequalities in disability is an important public health challenge. We examined work disability due to depression with four indicators of socioeconomic status.
METHODS: A prospective cohort study of 125 355 Finnish public sector employees was linked to national register data on work disability (>9 days) due to depressive disorders (International Classification of Diseases, codes F32-F34) from January 2005 to December 2011. Primary outcomes were the onset of work disability due to depressive disorders and, among those with such disability, return to work after and recurrent episodes of work disability due to depression.
RESULTS: We found a consistent inverse socioeconomic gradient in work disability due to depression. Lower occupational position, lower educational level, smaller residence size, and rented (vs. owner-occupied) residence were all associated with an increased risk of work disability. Return to work was slower for employees with basic education (cumulative odds ratio = 1.21, 95% CI: 1.05-1.39) compared to those with higher education. Recurrent work disability episodes due to depression were less common among upper-grade non-manual workers (the highest occupational group) than among lower-grade non-manual (hazard ratio = 1.16, 95% CI: 1.07-1.25) and manual (hazard ratio = 1.14, 95% CI: 1.02-1.26) workers.
CONCLUSIONS: These data from Finnish public sector employees show persistent socioeconomic inequalities in work disability due to depression from 2005 to 2011 in terms of onset, recovery and recurrence. - Articlede Freitas DA, Barbosa JA, Labuto G, Nocelli RCF, Carrilho ENVM.Environ Sci Pollut Res Int. 2022 Nov;29(53):79855-79865.The removal of the neonicotinoid and systemic pesticide thiamethoxam (TMX) from water and sugarcane juice by magnetic nanomodified activated carbon (AC-NP) is proposed. This adsorbent was synthesized and characterized by FTIR, XRD, and SEM, and TMX was quantified by high-performance liquid chromatography coupled to a diode array detector (HPLC-DAD). The AC-NP was efficiently synthesized using a co-precipitation method and the impregnation of magnetite (NP) in the activated carbon (AC) was assessed by the crystalline planes found in the AC-NP structure shown in the XRD diffractograms. The AC-NP FTIR analysis also indicated predominant bands of Fe-O stretching of the magnetite at 610-570 cm-1. Functional groups in AC and AC-NP were identified by absorption bands at 3550 and 1603 cm-1, characteristic of O-H and C = C, respectively. The TMX adsorption kinetics in sugarcane juice was the pseudo-second-order type with r2 = 0.9999, indicating a chemical adsorption process. The experimental sorption capacity (SCexp) for both TMX (standard) and TMX-I (insecticide) by AC-NP were 13.44 and 42.44 mg/g, respectively. Seven non-linear isotherm models (Langmuir, Freundlich, Dubinin-Radushkevich, Toth, Hill, Sips, and Redlich-Peterson) were fitted to the experimental adsorption data of TMX and TMX-I by AC-NP. Considering the standard error (SE), Freundlich, Langmuir, and Sips were the most appropriate models to describe the TMX adsorption, and Hill's best adjusted to TMX-I experimental data. The chromatographic method was highly satisfactory due to its high selectivity and recovery (91-103%). The efficiency of AC-NP in the sorption of TMX was confirmed by the excellent values of SCexp and sorption kinetics.
- ArticleYamashita A, Sakuno T, Watanabe Y, Yamamoto M.Cold Spring Harb Protoc. 2017 Sep 01;2017(9):pdb.top079855.Meiosis is a specialized cell cycle that generates haploid gametes from diploid cells. The fission yeast Schizosaccharomyces pombe is one of the best model organisms for studying the regulatory mechanisms of meiosis. S. pombe cells, which normally grow in the haploid state, diploidize by conjugation and initiate meiosis when starved for nutrients, especially nitrogen. Following two rounds of chromosome segregation, spore formation takes place. The switch from mitosis to meiosis is controlled by a kinase, Pat1, and an RNA-binding protein, Mei2. Mei2 is also a key factor for meiosis-specific gene expression. Studies on S. pombe have offered insights into cell cycle regulation and chromosome segregation during meiosis. Here we outline the current understanding of the molecular mechanisms regulating the initiation and progression of meiosis, and introduce methods for the study of meiosis in fission yeast.
- BookDonald E. Thomas, Jr., MD, FACP, FACR.Summary: "In this new, completely updated edition of The Lupus Encyclopedia, Dr. Thomas along with leading experts from around the globe detail everything you need to know about what lupus is and how autoimmune disorders affect the body and mind, the symptoms associated with lupus, what tests are needed to make a lupus diagnosis, how to find a specialist who can provide you with the best care, advice on obtaining the best treatments for your specific symptoms, and lifestyle factors that can help you avoid flare-ups"-- Provided by publisher
Contents:
0 Contributing Chapter Editors
0 List of Illustrations
0 List of Tables
0 Foreword
0 Preface
0 Acknowledgments
0 Part I
1 What Is Lupus and How Is It Diagnosed?
2 Other Autoimmune Diseases
3 What Causes Lupus?
4 Meaning of All Those Test Results
0 Part II
5 How SLE Affects the Body Directly
6 Constitutional Symptoms
7 Musculoskeletal System
8 Skin and Mucous Membranes
9 Blood and Lymph Systems
10 Respiratory System
11 Heart and Blood Vessels
12 Urinary System
13 Nervous System
14 Exocrine Gland System
15 Digestive System
16 Eyes
17 Endocrine System
18 Reproductive System and Pregnancy
19 Prognosis, Special Populations, Healthcare Disparities
20 Lupus in Children and Adolescents
0 Part III
21 Heart Attacks, Strokes, and Blood Clots
22 Infections
23 Cancer
24 Osteoporosis
25 Avascular Necrosis of Bone
26 Adrenal Insufficiency
27 Fibromyalgia
28 Gastroesophageal Reflux and Stomach Ulcers
0 Part IV
29 General Treatment of Lupus
30 Antimalarials
31 Steroids
32 Immunosuppressants
33 Biologic Agents
34 Newest FDA-Approved Drugs for Lupus
35 Other Therapies for SLE
36 Prescription Pain Medicines
37 Future Treatments for SLE
38 Non-drug Therapies for Lupus
39 Complementary (Integrative) Medicine
0 Part V
40 Understanding your Symptoms
41 Becoming Pregnant, Breast-Feeding, Contraception, Menopause Treatment
42 Preparing for Surgery and Travel
43 Communicating with your Provider
44 Lupus Secrets Checklist
0 Index.