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  • Article
    Alqahtani AM, Alshihri YD, Alhumaid AE, Al Nafaie MM, Alnaim AA.
    Cureus. 2025 Jan;17(1):e76929.
    Minimally invasive dentistry (MID) has revolutionized pediatric dental care by emphasizing the preservation of healthy tooth structures, reducing treatment-related trauma, and improving patient compliance. This narrative review explores advancements in MID techniques, including silver diamine fluoride (SDF), resin infiltration, atraumatic restorative treatment (ART), bioactive materials, laser-assisted therapies, and three-dimensional (3D) printing technologies. These approaches prioritize early diagnosis, prevention, and conservative management, aligning with patient-centered and sustainable practices. SDF demonstrates high efficacy in arresting caries progression but presents esthetic challenges due to discoloration. Resin infiltration provides esthetic and noninvasive treatment for white spot lesions, while ART offers cost-effective and child-friendly caries management in resource-limited settings. Bioactive materials support tissue regeneration, and laser technologies enable precise and painless procedures, although their adoption is limited by high costs and training requirements. Emerging tools, such as artificial intelligence and 3D printing, enhance diagnostic accuracy and treatment precision. Despite challenges related to cost, operator training, and infrastructure, MID techniques continue to evolve, offering promising solutions for pediatric dental care. Future research should focus on optimizing materials, improving accessibility, and integrating digital technologies to broaden the impact of minimally invasive approaches. This review highlights MID's transformative role in improving oral health outcomes and ensuring sustainable, patient-focused care for children.
    Digital Access Access Options
  • Article
    Oettl SK, Gerstmeier J, Khan SY, Wiechmann K, Bauer J, Atanasov AG, Malainer C, Awad EM, Uhrin P, Heiss EH, Waltenberger B, Remias D, Breuss JM, Boustie J, Dirsch VM, Stuppner H, Werz O, Rollinger JM.
    PLoS One. 2013;8(10):e76929.
    In vitro screening of 17 Alpine lichen species for their inhibitory activity against 5-lipoxygenase, microsomal prostaglandin E2 synthase-1 and nuclear factor kappa B revealed Cetrelia monachorum (Zahlbr.) W.L. Culb. & C.F. Culb. As conceivable source for novel anti-inflammatory compounds. Phytochemical investigation of the ethanolic crude extract resulted in the isolation and identification of 11 constituents, belonging to depsides and derivatives of orsellinic acid, olivetolic acid and olivetol. The two depsides imbricaric acid (4) and perlatolic acid (5) approved dual inhibitory activities on microsomal prostaglandin E2 synthase-1 (IC50 = 1.9 and 0.4 µM, resp.) and on 5-lipoxygenase tested in a cell-based assay (IC50 = 5.3 and 1.8 µM, resp.) and on purified enzyme (IC50 = 3.5 and 0.4 µM, resp.). Additionally, these two main constituents quantified in the extract with 15.22% (4) and 9.10% (5) showed significant inhibition of tumor necrosis factor alpha-induced nuclear factor kappa B activation in luciferase reporter cells with IC50 values of 2.0 and 7.0 µM, respectively. In a murine in vivo model of inflammation, 5 impaired the inflammatory, thioglycollate-induced recruitment of leukocytes to the peritoneum. The potent inhibitory effects on the three identified targets attest 4 and 5 a pronounced multi-target anti-inflammatory profile which warrants further investigation on their pharmacokinetics and in vivo efficacy.
    Digital Access Access Options
  • Book
    edited by Glenda C. Liell, Martin J. Fisher, and Lawrence F. Jones.
    Summary: "Challenging Bias in Forensic Psychological Assessment and Testing is a ground-breaking work that addresses the biases and inequalities within the field of forensic psychology. It gives valuable insights into individuals practices and wider criminal justice approaches at an international level, while providing tangible solutions to tackle the disparities"-- Provided by publisher.

    Contents:
    Part 1: Present day issues in forensic psychological assessment
    Introduction: Forensic Context Assessment
    Reliability, Validity, & Current Challenges / Glenda Liell, Martin Fisher and Lawrence Jones with Lorraine Hough
    Challenging Bias in the Forensic Context: Lived Experiences / Palwinder Athwal-Kooner, Martine Ratcliffe & Ana Da Silva
    The Role of Dynamic Risk Factors in Forensic Assessment and Treatment planning / Roxanne Hefferman and Tony Ward
    Why dynamic risk factors cannot be applied universally: Their normative nature and the importance of cultural awareness in risk assessment and intervention / Stefanie Schmidt, Roxanne Heffernan & Tony Ward
    The Validity of Reconviction as a Proxy Measure for Re-offending: Interpreting Risk Measures and Research in the Light of False Convictions and Detection and Conviction Evasion Skills (DACES) and processes / Lawrence Jones, Martin Fisher and Glenda Liell
    Measuring what matters: Standardized risk levels for criminal recidivism risk / Daryl Kroner and R. Karl Hanson
    The Cumulative Modelling of Risk / Sean Hamilton & Mags O'Rourke
    What Works in the Digital Age? VR and Smartphone Applications for Forensic Psychology / Aniek M. Siezenga, Jean-Louis van Gelder & Job van der Schalk
    Assessment and Intervention Technologies in Juvenile Justice / Christopher M. King, Lauren Grove, Rachel Bomysoad, Kenny Gonzalez & Loumarie Vasquez.
    Implications and Considerations for Conducting Remote Forensic Evaluations in Underserved and Marginalized Communities / Ashley Batastini, Natalie Anumba, Michelle Guyon & Meera Patel
    Part 2: Forensic practice & working with biases
    Supervising Assessment Practice / Jason Davies
    The Power Threat Meaning Framework
    Implications for the Criminal Justice System / Jo Ramsden & Kerry Beckley
    Individual Bias in Forensic Practice / Todd Hogue & Mats Dernevik.
    Cultural bias in Forensic Assessment: Considerations and Suggestions / Andrew Day, Yilma Woldgabreal & Luke Butcher
    Personal Construct Psychology & Repertory Grids in Formulation / Nicholas Blagden & Adrian Needs.
    Using Social Media Data in Forensic Evaluations: Addressing Bias / Ashley Batastini, Madison Lord & Michael Vitacco.
    Part 3: Diversity & forensic populations theoretical and practical approaches
    Gender-sensitive violence risk assessment / Vivienne de Vogel
    Critical Reflection on Gender Identity Assessments with Trans and Gender Non-Binary individuals: Challenges, implications, and a newly proposed approach in Forensic Psychology / Sören Henrich.
    Neurodiversity Assessment In Forensic Contexts / Nancy Doyle, Lorraine Hough, Karen Thorne & Tanya Banfield.
    Risk Assessment in Offenders with Learning Disabilities / Emma Longfellow, Mark Callender & Rachel Hicks.
    How forensic practitioners may better understand neurodevelopmental disorders within forensic practice with a specific focus on ADHD and ASD / Rachel Worthington.
    Deafness in a forensic context / Mats Dernevik, Brendan Monteiro, Lorraine Hough & Elizabeth Kimber
    Criminally Diverse Offenders / Phillip Willmot
    Challenging Bias in the Assessment of Extremist Offending / Christopher Dean & Monica Lloyd.
    The Assessment of Psychopathy / Jake Seaward & Jenny Tew.
    Technological assessment methods: New directions in the assessment of sexual offending and sexualised violence / Derek Perkins and Ignazio Puzzo
    Future direction
    Challenging bias in cross-cultural forensic psychology assessment and testing: A summary perspective / Yilma Woldgabreal.
    Digital Access TandFonline 2022