Bookedited by Yubin Zhou and Kai Zhang.
Summary: "Optogenetics represents a breakthrough technology capable of dynamically modulating molecular and cellular activity in live cells with high precision. This transformative technology made it possible to reversibly interrogate protein actions, cellular events, and animal behaviors with a simple flash of light. Manipulating light's temporal and spatial profile enabled precise control of membrane potentials. This feature has inspired non-opsinbased optogenetics, which inherits the precise spatiotemporal resolution but expands the targets into a diverse pool of biomolecules such as membrane receptors, ion channels,kinases, GTPases, and transcription factors. This book is unique because it emphasizes the design and applications of opsin-free optogenetic tools."-- Provided by publisher.
Contents:
Optogenetic dissection of a two-component calcium influx pathway / Xiaoxuan Liu, Yingshan Wang, Yubin Zhou, and Guolin Ma
High-throughput engineering of a light-activatable Ca2 channel / Lian He, Liuqing Wang, and Youjun Wang
Optogenetic activation of TrkB signaling / Peiyuan Huang, Zhihao Zhao, Lei Lei, and Liting Duan
Spatiotemporal modulation of neural repair / Huaxun Fan, Qin Wang, Kai Zhang, and Yuanquan Song
Optogenetic control of neural stem cell differentiation / Yixun Su, Taida Huang, Kai Zhang, and Chenju Yi
An optogenetic toolbox for remote control of programmed cell death / Ningxia Zhang and Ji Jing
Control of protein levels in Saccharomyces cerevisiae by optogenetic modules that act on protein synthesis and stability / Sophia Hasenjäger, Jonathan Trauth, and Christof Taxis
Optogenetics as a tool to study neurodegeneration and signal transduction / Prabhat Tiwari and Nicholas S. Tolwinski
Opsin-free optogenetics : brain and beyond / Jongryul Hong, Yeonji Jeong, and Won Do Heo
Constructing a far-red light-induced split-Cre recombinase system for controllable genome
Engineering / Meiyan Wang, Jiali Wu, and Haifeng Ye
Tools and Technologies for Wireless and Non-invasive Optogenetics / Guangfu Wu, Vagif Abdulla, Yiyuan Yang, Michael Schneider, and Yi Zhang.