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  • Book
    Brenda A. Wilson, Malcolm E. Winkler, Brian T. Ho.
    Summary: "Completely revised and updated, and for the first time in stunning full-color, Bacterial Pathogenesis: A Molecular Approach, Fourth Edition, builds on the core principles and foundations of its predecessors while expanding into new concepts, key findings, and cutting-edge research, including new developments in the areas of the microbiome and CRISPR as well as the growing challenges of antimicrobial resistance. All-new detailed illustrations help students clearly understand important concepts and mechanisms of the complex interplay between bacterial pathogens and their hosts. Study questions at the end of each chapter challenge students to delve more deeply into the topics covered, and hone their skills in reading, interpreting, and analyzing data, as well as devising their own experiments. A detailed glossary defines and expands on key terms highlighted throughout the book. Written for advanced undergraduate, graduate, and professional students in microbiology, bacteriology, and pathogenesis, this text is a must-have for anyone looking for a greater understanding of virulence mechanisms across the breadth of bacterial pathogens."-- Provided by publisher.

    Contents:
    The power of bacteria
    Skin and mucosa: the first lines of defense against bacterial infections
    The innate immune system: always on guard
    The adaptive defenses: antibodies and cytotoxic T cells
    The microbiota of the human body: microbiomes and beyond
    Microbes and disease: establishing a connection
    Mechanisms of genetic modification and exchange: role in pathogen evolution
    Identification of virulence factors: measuring infectivity and virulence
    Identification of virulence factors: molecular approaches for bacterial factors
    Identification of virulence factors: molecular approaches for host factors
    Bacterial strategies for colonization and survival in the host
    Toxins and other toxic virulence factors
    Delivery of virulence factors
    Virulence regulation
    Antimicrobial compounds and their targets
    Antibiotic resistance
    Vaccination: a critical component of the modern medical armamentarium
    The gram-positive opportunistic pathogens
    The gram-negative opportunistic pathogens
    The changing roles of microbiologists in an age of bioterrorism and emerging diseases
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    QR201.B34 S24 2019
    1