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  • Article
    Yan X, Liu J, Huang J, Wang Y, Leng X, Li T, Ouyang H, Yan X, He S.
    Phytochemistry. 2022 Dec;204:113438.
    Five undescribed biscembranoids, bistrochelides H-L, along with four known biscembranoids, glaucumolides A-B and bistrochelides A-B, were isolated from the soft coral Sarcophyton serenei collected off the Xisha Island in the South China Sea. The structures of these compounds were elucidated by HRESIMS (high-resolution electrospray ionization mass spectroscopy) spectrometry, NMR (nuclear magnetic resonance) spectroscopy, X-ray diffraction analysis, electronic circular dichroism (ECD), and the comparison of their spectroscopic data with those reported in the literature. In bioassay, some compounds showed a strong inhibitory effect on osteoclast precursor cells at the concentration of 10 μM. Additionally, all compounds exhibited weakly antimicrobial activity against Vibrio harveyi.
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doi:10.1016/j.phytochem.2022.113438