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  • Book
    edited by Petros Levounis, M .D., M.A., Erin Zerbo, M.D., Rashi Aggarwal, M.D.
    Summary: Twenty concise chapters accessibly address a broad spectrum of topics, including the fundamentals of addiction; specific substances and addictive behaviors, including gambling disorder; and treatment approaches, including special issues with psychiatric and medical comorbidities.

    Contents:
    Neurobiology of addiction from reward to relief : the complex neuroadaptations underlying addiction
    Addiction assessment across settings of care : approaches for the twenty-first-century / Mirela Feurdean
    Dsm-5 diagnosis and toxicology / Petros Levounis, Lindsay Lynch
    Alcohol / Faye Chao, Nauman Ashraf
    Anabolic-androgenic steroids / Cheryl A. Kennedy, Tshering Bhutia
    Benzodiazepines / Vicki Kalira
    Caffeine / Grace Hennessy
    Cannabis / Michael A. Ketteringham
    Hallucinogens and dissociative drugs / C. Alexander Paleos
    Inhalants / Abigail J. Herron
    Opioids / Erin Zerbo, Rashi Aggarwal
    Stimulants / Douglas Opler, Shaojie Han
    Tobacco / Timothy Koehler Brennan, Annie Levesque, Caylin Riley
    Behavioral addictions : focus on gambling disorder / Timothy Fong
    Cognitive-behavioral therapy / Adam R. Demner
    Relapse prevention / Bernadine Han, Jonathan Avery
    Motivational interviewing / John Douglas
    Twelve-step programs and spirituality / J. David Stiffler, Emily Deringer
    Mindfulness and mentalization / Maryn Sloane
    Diet and exercise / Sonya Lazarevic, Alex Zaphiris.
    Digital Access PsychiatryOnline 2016
  • Article
    Kunin CM, Chesney RW, Craig WA, England AC, DeAngelis C.
    Pediatrics. 1978 Nov;62(5):751-60.
    Urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) was shown to be reproducible in random urine specimens when expressed as the ratio of NAG to milligrams of urinary creatinine. The enzyme/creatinine ratio in 815 healthy people was relatively constant throughout childhood and adult life except for the first two years after birth and in individuals 56 years or greater. High ratios in the young children may be explained by low urinary creatinine excretion probably related to small body mass and reduced glomerular filtration rate at this age. The ratio was increased in adult uremic patients and children and adults with a variety of neurologic and obstructive lesions of the voiding mechanism. The presence of bacteriuria did not appear to increase the ratio. Significant enzymuria (greater than 2 SD above the mean for age and sex) was detected in 38 of 81 children with well-characterized renal disease. Among patients with predominantly glomerular disorders there was a close relationship between activity of the disease and enzymuria. In patients with tubulointerstitial disease enzymuria was frequent even in the absence of proteinuria. One of the highest enzyme/creatinine ratios was observed in a child with cystinosis. These studies indicate that NAG enzymuria is a sensitive indicator of activity of renal disease and may prove to be a suitable screening test for significant renal disease or injury in childhood.
    Digital Access Access Options