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- BookTerje Sundstrøm [and more], editors.Summary: This book provides sound clinical guidance on the treatment of adults and children with severe head injuries, from the time of initial contact through to the rehabilitation center. Offers recommended diagnostic and therapeutic measures, and useful flow charts.
Contents:
Rotrauma research
Index monitoring
Monitoring microdialysis
Jugular bulb measurements (SJVO2)
Cerebral blood flow (CBF) and cerebral metabolic rate (CMR)
Transcranial Doppler (TCD)
Near infrared spectroscopy (NIRS) or cerebral oximetry
Clinical Neurophysiology: Evoked Potentials
Clinical Neurophysiology: Continous EEG Monitoring
Imaging of severe traumatic brain injury in the neurointensive care unit
Serum protein biomarkers in the management of severe traumatic brain injury
Cardiopulmonary aspects
Renal aspects
Neuroendocrine aspects
Part VIII Treatment in neurointensive care
Guidelines for treatment of patients with severe traumatic brain injury
The Lund therapy: a physiological approach
Pharmacological neuroprotection
Subacute surgery in neurointensive care
Management of extracranial injuries
CSF Drainage
Hyperventilation
Osmotherapy
Barbiturates for ICP management
Management of fluid and electrolyte disturbances
Sedation: including pain treatment and withdrawal symptoms
Nutrition
Management of CNS-related infection
Management of extracranial infections
Temperature management
Seizures
Paroxysmal sympathetic hyperactivity
Prophylaxis against venous thromboembolism
Coagulopathy (bleeding tendency)
Corticosteroids
Management of acute psychiatric problems
Part IX Rehabilitation and follow-up
Rehabilitation after severe TBI
Long-term follow-up
Part X Outcome and prognosis
General overview
Somatic consequences
Neuropsychiatric consequences
Neuropsychological perspectives
Neurosurgical challenges
Minimally conscious and vegetative state
Specific peadiatric concerns
Socioeconomic consequences
Subacute MR Imaging: Traumatic axonal injury, brain stem lesions and prognostic factors
Neurodegeneration and dementia
Part XI Research in severe TBI
The neurointensive care unit as a platform for advanced clinical research
Current state-of-the-art in neu.Digital Access Springer 2020 - ArticleMuscoplat CC, Rakich PM, Thoen CO, Johnson DW.Infect Immun. 1978 Jun;20(3):627-31.Incubation of Mycobacterium bovis-sensitized bovine peripheral blood lymphocytes with concanavalin A or M. bovis purified protein derivative and indomethacin caused a consistent, statistically significant increase in [3H] thymidine uptake as compared to cultures without indomethacin. The kinetics of the response showed that indomethacin must be added to lymphocyte cultures within hours after mitogen or antigen addition for enhancement of [3H]thymidine uptake to occur. Lymphocyte blastogenic responses to purified protein derivative were enhanced in both normal and M. bovis-sensitized lymphocyte cultures. However, enhancement of sensitized lymphocyte responses was significantly (P less than 0.01) greater than that in normal animals. Additionally, indomethacin treatment of M. bovis-sensitized guinea pigs singnificantly augmented delayed skin reactions to tuberculin. Delayed hypersensitive skin reactions were only enhanced when indomethacin was administered simultaneously with tuberculin.