BookKakoli Bose, Pradip Chaudhari, editors.
Summary: Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
Contents:
Cancer Biology and its Treatment Modalities: A Brief Historical Perspective
Emerging Peptide Technologies in Cancer Therapy
Protein Palmitoylation in Cancer
Advances in Mass Spectrometry-Based Proteomics and its Application in Cancer Research
Apoptosis in Cancer Cell Signaling and Current Therapeutic Possibilities
Integration of Evolutionary Theory into Cancer Biology and Caspase Signaling
Emerging Epigenetic Targets and their Implications in Cancer Therapy
Anti-cancer Immunotherapy: Prospects and Challenges
Preclinical Animal Models for Cancer Research and Drug Discovery
Dysregulated Signaling Pathways in Cancer: Approaches and Applications
Analysing Cancer Signalling Pathways: A Structural Bioinformatics Approach
Targeting Cancer from a Structural Biology Perspective
Applications of NMR in Cancer Research
Proteomics for Cancer: Approaches and Challenges
Applications of Microarray in Cancer Cell Signaling Pathways
Nanotechnology: The Future for Cancer Treatment
Preclinical Non-invasive Imaging in Cancer Research and Drug Discovery: An Overview
Genomic Applications and Insights in Unravelling Cancer Signalling Pathways
Applications of Computational Systems Biology in Cancer Signaling Pathways
New Emerging Molecules in Cancer Research Which Hold Promise in Current Era.