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  • Book
    edited by Andreas Kuhn.
    Summary: This book provides an up-to-date overview of the architecture and biosynthesis of bacterial and archaeal cell walls, highlighting the evolution-based similarities in, but also the intriguing differences between the cell walls of Gram-negative bacteria, the Firmicutes and Actinobacteria, and the Archaea. The recent major advances in this field, which have brought to light many new structural and functional details, are presented and discussed. Over the past five years, a number of novel systems, e.g. for lipid, porin and lipopolysaccharide biosynthesis have been described. In addition, new structural achievements with periplasmic chaperones have been made, all of which have revealed amazing details on how bacterial cell walls are synthesized. These findings provide an essential basis for future research, e.g. the development of new antibiotics. The books content is the logical continuation of Volume 84 of SCBI (on Prokaryotic Cytoskeletons), and sets the stage for upcoming volumes on Protein Complexes.

    Contents:
    The bacterial cell wall and membrane
    a treasure chest for antibiotic targets
    Lipopolysaccharide biosynthesis and transport to the outer membrane of Gram-negative bacteria
    Lipoproteins: structure, function, biosynthesis
    Outer membrane porins
    Peptidoglycan
    The Periplasmic Chaperones Skp and SurA
    Bacterial signal peptidases
    Carbohydrate Transport by Group Translocation: The Bacterial Phosphoenolpyruvate : Sugar Phosphotransferase System
    Secondary active transporters
    Respiratory membrane protein complexes convert chemical energy
    Inner membrane translocases and insertases
    The biosynthesis and structures of bacterial pili
    Cell Walls and Membranes of Actinobacteria
    Archaeal cell walls.
    Digital Access Springer 2019