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- Bookedited by Mouldy Sioud.Contents:
RNA interference : mechanisms, technical challenges, and therapeutic opportunities / Mouldy Sioud
Nanostructured RNAs for RNA interference / Yuko Nakashima [and others]
One long oligonucleotide or two short oligonucleotides based shRNA construction and expression / Xue-jun Wang and Sheng-qi Wang
PLGA microspheres encapsulating siRNA / Giuseppe De Rosa and Giuseppina Salzano
Magnetic nanoparticle and magnetic field assisted siRNA delivery in vitro / Olga Mykhaylyk [and others]
Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation / Mouldy Sioud
Delivery of siRNAs to cancer cells via bacteria / Omar Ahmed, Andrea Krühn, and Hermann Lage
Microwell array-mediated delivery of lipoplexes containing nucleic acids for enhanced therapeutic efficacy / Yun Wu, Daniel Gallego-Perez, and L. James Lee
Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy / Karin Zins [and others]
Targeted in vivo delivery of siRNA and an endosome- releasing agent to hepatocytes / Magdolna G. Sebestyén [and others]
Cell-internalization SELEX : method for identifying cell- internalizing RNA aptamers for delivering siRNAs to target cells / William H. Thiel [and others]
Strategies for siRNA navigation to desired cells / Mouldy Sioud
Use of guanidinopropyl-modified siRNAs to silence gene expression / Maximilian C.R. Buff [and others]
Therapy of respiratory viral infections with intranasal siRNAs / Sailen Barik and Patrick Lu
Engineering therapeutic cancer vaccines that activate antitumor immunity / Per Ole Iversen and Mouldy Sioud
Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses / Mouldy Sioud, Anne Mobergslien, and Stein Sæbøe-Larssen
Targeting bcr-abl transcripts with siRNAs in an imatinib- resistant chronic myeloid leukemia patient : challenges and future directions / Michael Koldehoff
Facile method for interfering with off-target silencing mediated by the sense strand / Anne Mobergslien and Mouldy Sioud
Overcoming the challenges of siRNA activation of innate immunity : design better therapeutic siRNAs / Mouldy Sioud
Gene silencing in vitro and in vivo using intronic microRNAs / Jia Han Deng [and others]
In silico identification of novel endo-siRNAs / Andrew Schuster [and others]
Computer-assisted annotation of small RNA transcriptomes / Nicole Ortogero [and others]
miR-CATCH : microRNA capture affinity technology / Sebastian Vencken [and others]
Roles of MicroRNAs in cancers and development / Shigeru Takasaki
Targeting microRNAs to withstand cancer metastasis / Valentina Profumo [and others]
Urinary microRNAs as a new class of noninvasive biomarkers in oncology, nephrology, and cardiology / Hana Mlcochova [and others]
Magnetic bead-based isolation of exosomes / Morten P. Oksvold, Axl Neurauter, and Ketil W. Pedersen
Modified 2'-ribose small RNAs function as toll-like receptor-7/8 antagonists / Mouldy Sioud.Digital Access Springer 2015 - ArticleRivera H, Hernandez A, Martinez y Martinez R, Plascencia L, Cuevas A, Cantu JM.Ann Genet. 1979;22(4):225-7.A 5 10/12 year-old boy with a 47,XYY karyotype, micropenis, scrotal hypospadias and right testicular regression is described. Normal for age basal plasma testosterone levels which increased after hCG stimulation were interpreted as an adequate response of the left testicular Leydig cells. The review of similar cases did not permit definite conclusions concerning the relationship between the abnormal genitalia and the XYY karyotype.