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- BookAlessia Minicozzi.Summary: "When physicians complete their training, they are given a title of "attending" and given full authority to care for patients. Many researchers assume their training process is complete. However, through a sociological ethnographic study of first-year attending at a prestigious pediatric hospital, many unresolved issues emerge: developing a style of doctoring, acquiring an authoritative role, dealing with professional uncertainty, malpractice, balancing work and family life. Understanding the first-year attending's socialization process can help medical educators expand their body of knowledge and improve patient care."
- ArticleGregory H, Walsh S, Hopkins CR.Gastroenterology. 1979 Aug;77(2):313-8.Urogastrone, a peptide isolated from human urine, is known to cause inhibition of gastric acid secretion and proliferation of fibroblasts in culture; furthermore immunofluorescent localization techniques show it to be present in submandibular and Brunner's glands. Serum, saliva, and gastric juice samples have now been fractionated upon Sephadex G-200 and G-50 and the immunoreactive urogastrone located using a specific radioimmunoassay. Biologic activity was shown by mitogenic studies with 3T6 fibroblasts. In serum, the major immunoreactive component was ca. 1-2 X 10(5) daltons, but trypsin treatment then gave a smaller biologically active species in the same position as pure urogastrone on Sephadex G-50. Both saliva and gastric juice showed major components at the position defined by urogastrone, and these also stimulated the uptake of [H]thymidine into the fibroblasts. It is concluded that a urogastrone-like molecule can be released enzymically from a high molecular weight serum precursor and that the small biologically active peptide is also a normal component of saliva and gastric juice.