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- ArticleRechardt L, Kanerva L, Hervonen H.Histochemistry. 1977 Dec 28;54(4):339-43.Potassium permanganate fixative is usually employed at pH 7.0. At this pH the amines in the granules of the adrenal medullary cells do not react with permanganate. When the pH was adjusted to 5.0, electron dense precipitates were seen in the amine granules of part of the medullary cells, probably noradrenalin containing cells.