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  • Book
    edited by Anna Porwit, Marie Christine Béné.
    Summary: Master implementation of the techniques of flow cytometry in diagnosing complex haematological diseases and malignancies in patients, worldwide. Featuring World Health Organization recommendations on pre-analytical steps, instrument settings and panel construction, this invaluable manual offers invaluable support for those researching, practising and analyzing the cause of hematological malignancies. Authored by leading experts, this book puts flow-cytometry into everyday context. With a focus on multicolour panels, the manual provides readers an experienced understanding of effective, implementation techniques. Practitioners of all levels are offered a background in a variety of diseases presented alongside the most current methodology. Wide-ranging and comprehensive; detailed images of healthy blood, bone marrow and lymph-nodes are illustrated throughout, allowing for effective diagnosis. Through engaging with differential diagnoses, the manual offers an understanding of similar symptoms and mimicking malignancies, avoiding inaccurate results. Featuring in-depth descriptions of chronic diseases; users can reach accurate diagnosis, first time.
    Digital Access Cambridge 2018
  • Article
    Cowley AW.
    Cardiovasc Clin. 1978;9(1):1-22.
    Present understanding of the physiology of arterial pressure regulation indicates that the renal-body fluid volume system determines the level at which the mean pressure resides over long periods of time. The relationships between blood volume, and size and compliance of the entire vascular system, and intrinsic regulation of tissue blood flow determine the sequence of observed changes in cardiac output and total peripheral resistance. Current evidence is compatible with the concept that functional changes in the renal vasculature or tubular system, either intrinsic or extrinsic in origin, reflect the final common pathway in the genesis of all forms of experimental and human hypertension. At the present time the nature of these renal changes appears to alter the fundamental relationships between renal perfusion pressure and sodium and water excretion. One of the major challenges in the field of hypertension today is to test the hypothesis that changes in renal function, either extrinsic or intrinsic in form, are involved in all forms of hypertension.
    Digital Access Access Options