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  • Book
    Auguste H. Fortin, VI, MD, MPH, Professor of Medicine Division of General Internal Medicine, ... Show More Yale University School of Medicine, Director of Psychosocial Communication, Yale Primary Care Internal Medicine Residency Program, New Haven, Connecticut [and four others].
    Summary: "A comprehensive, evidence-based introduction to the principles and practices of patient communication in a clinical setting Smith's Patient-Centered Interviewing, Fourth Edition presents a step-by-step methodology for mastering every aspect of the medical interview. Readers will learn how to confidently obtain from patients accurate biomedical facts, as well as critical personal, social, and emotional information, allowing them to make a precise diagnosis, develop effective treatment plans, and forge strong clinician-patient relationships. The most evidence-based guide available on the topic, Smith's Patient-Centered Interviewing, Fourth Edition applies the proven 5-step approach, which integrates patient- and clinician-centered skills to improve effectiveness without adding extra time to the interview duration. The book's user-friendly design features icons, boxed case vignettes, and use of color to highlight key points, and pedagogy includes learning an practice exercises in each chapter"-- Provided by publisher. "Our goal in this text is to present in a logical, step-by-step fashion the behaviors that are necessary to conduct an effective and efficient biopsychosocial interview. Interviewing is the most important and most difficult skill learners must master in their clinical careers. The book is designed for learners in medicine, advanced-practice nursing, physician assistant, and other health-related disciplines where communication and relational skills are central"-- Provided by publisher.
    Digital Access AccessMedicine 2019
  • Article
    Hall RM, Mattick JS, Nagley P, Cobon GS, Eastwood FW, Linnane AW.
    Mol Biol Rep. 1977 Dec;3(6):443-9.
    We have studied the effects on the yeast mitochondrial genome of four analogues of ethidium bromide, in which the phenyl moieyt has been replaced by linear alkyl chains of lengths varying from seven to fifteen carbon atoms. These analogues are more efficient than ethidium bromide in inducing petite mutants in Saccharomyces cervisiae. The drugs also cause a loss of mtDNA from the cells in vivo; however these analogues are in fact less effective inhibitors of mitochondrial DNA replication per se, as shown by direct in vitro studies. It is concluded that these analogues are more efficient than ethidium bromide in causing the fragmentation of mitochondrial DNA in S. cervisiae.
    Digital Access Access Options