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- ArticleKleinhans D, Knoth W.Arch Dermatol Res (1975). 1977 May 27;258(3):231-4.In 6 cases of granuloma anulare direct immunofluorescence studies were carried out with anti-fibrinogen and anti-immunoglobulin sera. Fibrin deposition was found in all lesions. The result is discussed with reference to local fibrinolysis.