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- BookCharlotte DeCroes Jacobs.Summary: "He first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS"-- Provided by publisher.
Contents:
Prologue: Two plagues
Born to serve
Finding his place
A wedding and a war
Joining the fight against influenza
Vaccine neophyte
Pittsburgh's virgin territory
Polio
The chosen
Ready to run
Research sub rosa
Out of his hands
The world's largest clinical trial
Relief from fear
The Cutter affair
Fame and its consequences
Act II
Two cultures under one roof
The price of a masterpiece
Seeking Shangri-La
A trouble marriage
Harnessing the immune system
A most unusual arrangement
Salk unfolding
Fall from grace
Final fling
Marginalized
The swine flu snafu
Return to the polio vaccine controversy
A Trojan horse
Disciples, sycophants, and lovers
AIDS: Salk's next mountain
Unbowed. - ArticleInnemee HC, van Ommeren JD, van Zwieten PA.Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Nov;212(1):11-8.The influence of clonidine on intraocular pressure was studied in chloralose-anesthetized cats. The cats were subjected to unilateral cervical sympathectomy, either acute or chronic. The drug was injected either intravenously or into the left vertebral artery. With the aim of investigating the role of the sympathetic nervous system in the central IOP-lowering effect of clonidine, the fall in IOP induced by the drug in these preparations was compared to the decrease in ocular pressure caused by clonidine in intact cats. An enhanced depressor effect in both eyes of unilaterally sympathectomized cats became evident after the intravenous injection of clonidine. In contrast, the effect of central administration was similar or even smaller than in intact cats. We conclude that the central IOP-lowering effect of clonidine is diminished after cervical sympathectomy, indicating that the peripheral sympathetic nervous system is the efferent pathway of this centrally initiated effect.